Evidence map›Paper›PMID 34616655›Full record

ReviewWorld journal of critical care medicine2021

Role of proning and positive end-expiratory pressure in COVID-19.

Kejal D Gandhi, Munish Sharma, Pahnwat Tonya Taweesedt, Salim Surani

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. CPAP vs HFNC in treatment of patients with COVID-19 ARDS: A retrospective propensity-matched study.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kejal D GandhiDepartment of Medicine, Georgetown University/Medstar Washington Hospital Center, Washigton, DC 20010, United States.
Munish SharmaDepartment of Medicine, Corpus Christi Medical Center, Corpus Christi, TX 78412, United States.
Pahnwat Tonya TaweesedtDepartment of Medicine, Corpus Christi Medical Center, Corpus Christi, TX 78412, United States.
Salim SuraniDepartment of Medicine, Texas A&M University, Corpus Christi, TX 78404, United States. srsurani@gmail.com.
Texas A&M University – Corpus Christi · USWashington Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel coronavirus, which was declared a pandemic by the World Health Organization in early 2020 has brought with itself major morbidity and mortality. It has increased hospital occupancy, heralded economic turmoil, and the rapid transmission and community spread have added to the burden of the virus. Most of the patients are admitted to the intensive care unit (ICU) for acute hypoxic respiratory failure often secondary to acute respiratory distress syndrome (ARDS). Based on the limited data available, there have been different opinions about the respiratory mechanics of the ARDS caused by coronavirus disease 2019 (COVID-19). Our article provides an insight into COVID-19 pathophysiology and how it differs from typical ARDS. Based on these differences, our article explains the different approach to ventilation in COVID-19 ARDS compared to typical ARDS. We critically analyze the role of positive end-expiratory pressure (PEEP) and proning in the ICU patients. Through the limited data and clinical experience are available, we believe that early proning in COVID-19 patients improves oxygenation and optimal PEEP should be titrated based on individual lung compliance.

Indexed as

Acute respiratory distress syndromeCOVID-19Intensive care unitPositive end-expiratory pressureProningVentilation management

Identifiers

PMID34616655
PMCPMC8462021
OpenAlexW3200396784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.