ArticleActa radiologica open2021
Diffusion-weighted MR imaging in chronic non-bacterial osteitis: Proof-of-concept of the apparent diffusion coefficient as an outcome measure.
Article in Acta radiologica open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors at 3 institutions in 1 country.
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Abstract
backgroundThe apparent diffusion coefficient (ADC), as determined by whole-body diffusion-weighted MRI, may be useful as an outcome measure for monitoring response to treatment in chronic non-bacterial osteitis. PURPOSE: To test and demonstrate the feasibility of ADC-measurement methods for use as outcome measure in chronic non-bacterial osteitis. MATERIALS AND
methodsUsing data from a randomized pilot study, feasibility of change-score ADC between baseline and second MRI (ΔADC
results12 subjects were enrolled, and MRI was performed at baseline and weeks 12 and 36. Pearson correlation was high (
conclusionADC change-score as outcome measure was feasible, and the single-slice per lesion ROI setting performed almost equally to whole-lesion setting resulting in reduced assessment time.
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