ArticleOxidative medicine and cellular longevity2021
Influence of Maternal Infection and Pregnancy Complications on Cord Blood Telomere Length.
Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Maternal Lifestyle During Pregnancy and Its Influence on Offspring's Telomere Length.Life (Basel, Switzerland) · 2025Review
- Prenatal irisin is inversely related to the term placental telomere length.BMC research notes · 2025Article
- Infant buccal telomere length: associations with maternal distress in pregnancy and offspring temperament.Frontiers in public health · 2025Article
- Association Between Adverse Early Life Factors and Telomere Length in Middle and Late Life.Innovation in aging · 2024Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExposure to suboptimal intrauterine environment might induce structural and functional changes that can affect neonatal health. Telomere length as an important indicator of cellular health has been associated with increased risk for disease development.
objectivesThis study was aimed to examine the independent and combined effects of maternal, obstetric, and foetal factors on cord blood telomere length (TL).
methodsPregnant women at the gestational age of 20
resultsA total of 753 pregnant women (average age: 32.18 ± 4.51 years) were recruited. The prevalence of maternal infection, anaemia, and hypertension during pregnancy was 30.8%, 30.0%, and 6.0%, respectively. The adjusted regression model displayed that maternal infection was negatively associated with cord blood TL (
conclusionsThis study consolidates evidence on the impact of adverse intrauterine environment at the cellular level. Maternal infection was significantly associated with shorter cord blood TL in a unique manner such that its presence may critically determine the susceptibility of telomere to other factors.
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