Evidence map›Paper›PMID 34616353›Full record

ArticleFrontiers in neurology2021

Dual-Antiplatelet Therapy May Not Be Associated With an Increased Risk of In-hospital Bleeding in Patients With Moderate or Severe Ischemic Stroke.

Ossama Khazaal, Aaron Rothstein, Muhammad R Husain, Matthew Broderick, Daniel Cristancho, Sahily Reyes-Esteves, Farhan Khan, Christopher G Favilla, Steven R Messé, Michael T Mullen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ossama KhazaalDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
Aaron RothsteinDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
Muhammad R HusainDepartment of Neurology, Camden Clark Medical Center/WVU Medicine, Parkersburg, WV, United States.
Matthew BroderickDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
Daniel CristanchoDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
Sahily Reyes-EstevesDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
Farhan KhanDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
Christopher G FavillaDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
Steven R MesséDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
Michael T MullenDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
University of Pennsylvania · USWest Virginia University Hospitals · US

Funding

Neurologic Clinical Epidemiology Training ProgramT32NS061779 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Andrea Lauren Christman Schneider, Allison Willis · 2008 to 2026
$4.6M
The Philadelphia Regional Stroke Trials Network Coordinating Center (PRSTNCC)U24NS107224 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Brett Lee Cucchiara · 2018 to 2026
$3.2M
NINDS NIH HHS T32 NS061779NINDS NIH HHS U24 NS107224
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bleeding ratebleeding riskdual antiplatelet therapyhemorrhagic transformationmoderate strokesecondary preventionsevere stroke

Identifiers

PMID34616353
PMCPMC8488084
OpenAlexW3200742618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.