Evidence map›Paper›PMID 34616179›Full record

ArticleCancer management and research2021

Clinical Characteristics and Therapeutic Outcomes of Metastatic Peritoneal Carcinomatosis in Non-Small-Cell Lung Cancer.

Tetsuo Tani, Ichiro Nakachi, Shinnosuke Ikemura, Shigenari Nukaga, Keiko Ohgino, Aoi Kuroda, Hideki Terai, Keita Masuzawa, Taro Shinozaki, Kota Ishioka and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 2 countries.

Tetsuo TaniDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-5719-2697
Ichiro NakachiDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-3930-9318
Shinnosuke IkemuraDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Shigenari NukagaDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Keiko OhginoDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Aoi KurodaDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Hideki TeraiDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Keita MasuzawaDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Taro ShinozakiDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Kota IshiokaDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Yohei FunatsuDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Hidefumi KohDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Koichi FukunagaDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0001-7460-1990
Kenzo SoejimaDepartment of Medicine, Keio University School of Medicine, Tokyo, Japan.
Keio Lung Oncology Group (KLOG)
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetastatic peritoneal carcinomatosis (MPC) is not common in patients with non-small cell lung cancer (NSCLC), and the clinical characteristics and treatment outcomes are still unclear. PATIENTS AND

methodsWe recruited 46 NSCLC patients with MPC at Keio University and affiliated hospitals (Keio Lung Oncology Group) between January 2011 and December 2017, then retrospectively investigated their clinical characteristics and the impact of treatment interventions on their survival.

resultsThe profile of histological subtype was predominantly adenocarcinoma and 15 patients harbored driver oncogenes. Univariate and multivariate analysis demonstrated that performance status and the presence of a driver oncogene were significantly associated with the prolonged overall survival (OS). Regarding treatment, the median OS in the treatment group (9.3 months) was significantly longer than in the best supportive care group (1.3 months) (P < 0.0001).

conclusionThe prognosis of MPC in NSCLC patients who receive only the best supportive care is poor, but therapeutic intervention may improve prognosis.

Indexed as

EGFRintraperitoneal disseminationmalignant ascitesmetastatic peritoneal carcinomatosisNSCLCperitoneal nodule

Identifiers

PMID34616179
PMCPMC8487800
OpenAlexW3203691320

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.