Evidence map›Paper›PMID 34616176›Full record

ArticleInternational journal of general medicine2021

Triglyceride-Glucose Index as a Novel Biomarker in the Occurrence of Kidney Stones: A Cross-Sectional Population-Based Study.

Hua Jiang, Lili Li, Jing Liu, Bin Xu, Shuqiu Chen, Weidong Zhu, Ming Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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  12. [Association between the triglyceride-glucose index and the incidence of nephrolithiasis in male individuals].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hua JiangDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, People's Republic of China.
Lili LiDepartment of Periodontology, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, 210009, People's Republic of China.
Jing LiuDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, People's Republic of China.
Bin XuDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, People's Republic of China.
Shuqiu ChenDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, People's Republic of China.
Weidong ZhuDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, People's Republic of China.
Ming ChenDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, 210009, People's Republic of China.ORCID 0000-0002-3572-6886
Zhongda Hospital Southeast University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTriglyceride-glucose (TyG) index has been considered as the reliable marker of insulin resistance (IR), which is one risk factor of kidney stone. This study aimed to evaluate the TyG index in the occurrence of kidney stones among the United States (US) population.

methodsParticipants who received assessment were retrieved from the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2018. The logistic regression analysis was conducted to assess the relationship between the TyG index and kidney stones occurrence. A 1:1 matched-pair analysis was established to optimize the bias in kidney stones by propensity score matching (PSM). The dose-response curve was performed to verify the association between the TyG index and risk of kidney stones.

resultsOf the 14,158 eligible enrolled participants, 1346 (9.5%) self-reported a history of kidney stones. All participants were divided into two groups (high TyG index group and low TyG index group) based on the median TyG index. The dose-response curve exhibited a positive non-linear correlation between the TyG index and kidney stones risk. High TyG index was related to increased kidney stones occurrence in participants, with adjusted odds ratios (AOR) of 1.14 (95% confidence intervals (CI): 1.01-1.30,

conclusionThe TyG index was independently associated with kidney stones and would be a novel biomarker in predicting occurrence for clinical decision.

Indexed as

cross-sectionalinsulin resistancekidney stoneNational Health and Nutrition Examination Surveytriglyceride–glucose index

Identifiers

PMID34616176
PMCPMC8487863
OpenAlexW3202415357

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.