ArticleNature2021
An atlas of gene regulatory elements in adult mouse cerebrum.
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Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.
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140citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
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Who cites it
140 citing papers in PubMed, 199 citations in OpenAlex.
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- MethyAnno: An Interpretable Automated Annotation Method Leveraging Multi-Scale Information and Metric Learning Framework for scDNAm Data.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Single-cell analysis of the epigenome and 3D chromatin architecture in the human retina.Science advances · 2026Article
- Genomic sequence evolution underlying human neocortical interareal diversification.Genome biology · 2026Article
- Fine-mapping candidate neuropsychiatric regulatory variants using cell type-aware comparative genomics.bioRxiv : the preprint server for biology · 2026Article
- SpaDC enables sequence-based integrative analysis and regulatory inference of spatial chromatin accessibility data.Communications biology · 2026Article
- The molecular asynchrony of single cells.bioRxiv : the preprint server for biology · 2026Article
- Transcription initiation profiling defines the regulatory logic of astrocyte gene regulation.bioRxiv : the preprint server for biology · 2026Article
- Spatially tunable multiomic sequencing using light-driven combinatorial barcoding of molecules in tissues.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- CREsted: modeling genomic and synthetic cell-type-specific enhancers across tissues and species.Nature methods · 2026Article
- Spatially decoding genotype-associated epigenetic landscapes in human lymphoma FFPE tissues via epi-Patho-DBiT.Nature communications · 2026Article
- A Community Standard Multispecies Cell Atlas of the Basal Ganglia.bioRxiv : the preprint server for biology · 2026Article
- Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease.Genome research · 2026Article
- Single-cell epigenomics uncovers heterochromatin instability and transcription factor dysfunction during mouse brain aging.Cell reports · 2026Article
- Boolean logic links chromatin accessibility states to gene expression variability across cell types.Nucleic acids research · 2026Article
- Single-cell spatial map of cis-regulatory elements for disease-related genes in the macaque cortex.Nature communications · 2026Article
- Article
- Single-cell multiomic human brain atlas reveals regulatory drivers of cortical regionality.Nature communications · 2026Article
80 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors at 5 institutions in 2 countries.
Yang Eric Li *Ludwig Institute for Cancer Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6997-6018
Sebastian Preissl *Department of Cellular and Molecular Medicine, Center for Epigenomics, University of California San Diego, School of Medicine, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-8971-5616
Xiaomeng HouDepartment of Cellular and Molecular Medicine, Center for Epigenomics, University of California San Diego, School of Medicine, La Jolla, CA, USA.
Ziyang ZhangLudwig Institute for Cancer Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-5870-704X
Kai ZhangLudwig Institute for Cancer Research, La Jolla, CA, USA.
Yunjiang QiuLudwig Institute for Cancer Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-0539-9714
Olivier B PoirionDepartment of Cellular and Molecular Medicine, Center for Epigenomics, University of California San Diego, School of Medicine, La Jolla, CA, USA.
Bin LiLudwig Institute for Cancer Research, La Jolla, CA, USA.
Joshua ChiouBiomedical Sciences Graduate Program, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-4618-0647
Hanqing LiuGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Antonio Pinto-DuarteComputational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-2215-7653
Naoki KuboLudwig Institute for Cancer Research, La Jolla, CA, USA.
Xiaoyu YangInstitute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.
Rongxin FangLudwig Institute for Cancer Research, La Jolla, CA, USA.
Xinxin WangDepartment of Cellular and Molecular Medicine, Center for Epigenomics, University of California San Diego, School of Medicine, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6393-2276
Jee Yun HanDepartment of Cellular and Molecular Medicine, Center for Epigenomics, University of California San Diego, School of Medicine, La Jolla, CA, USA.
Jacinta LuceroComputational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Yiming YanLudwig Institute for Cancer Research, La Jolla, CA, USA.
Michael MillerDepartment of Cellular and Molecular Medicine, Center for Epigenomics, University of California San Diego, School of Medicine, La Jolla, CA, USA.
Samantha KuanLudwig Institute for Cancer Research, La Jolla, CA, USA.
David GorkinDepartment of Cellular and Molecular Medicine, Center for Epigenomics, University of California San Diego, School of Medicine, La Jolla, CA, USA.
Kyle J GaultonDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-1318-7161
Yin ShenInstitute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-9901-5613
Michael NunnGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Eran A MukamelDepartment of Cognitive Science, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-3203-9535
M Margarita BehrensComputational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-7168-8186
Joseph R EckerGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-5799-5895
Bing RenLudwig Institute for Cancer Research, La Jolla, CA, USA. biren@health.ucsd.edu.ORCID http://orcid.org/0000-0002-5435-1127
University of California San Diego · USLudwig Cancer Research · USSalk Institute for Biological Studies · USUniversity of California, San Francisco · USLudwig Cancer Research · BE
Funding
Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Ye Zheng · 1985 to 2026
$82.8MGeneration of novel cell type specific mouse genetic toolsU19MH114830 · NIMH · ALLEN INSTITUTE · PI ZENG, HONGKUI · 2017 to 2021
$64.7MMolecular SignaturesU19MH114831 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI CALLAWAY, EDWARD M, ECKER, JOSEPH R · 2017 to 2021
$24.6MIllumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600kREGULATION OF CORTICAL PHENOTYPE BY BASAL FOREBRAINF30MH011483 · NIMH · UNIVERSITY OF CALIFORNIA IRVINE · PI HA, DUN H · 1997 to 1999
–Howard Hughes Medical InstituteNCI NIH HHS P30 CA014195NIH HHS S10 OD026929NIMH NIH HHS F30 MH011483NIMH NIH HHS U19 MH114830NIMH NIH HHS U19 MH114831
Abstract
The mammalian cerebrum performs high-level sensory perception, motor control and cognitive functions through highly specialized cortical and subcortical structures
Indexed as
AnimalsAtlases as TopicCerebrumChromatinChromatin Assembly and DisassemblyGene Expression RegulationGenetic Predisposition to DiseaseHumansMaleMiceMice, Inbred C57BLNervous System DiseasesNeurogliaNeuronsRegulatory Sequences, Nucleic AcidSequence Analysis, DNAChromatin
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