ArticleNature2021
Comparative cellular analysis of motor cortex in human, marmoset and mouse.
Erratum issuedOpen access · hybridAbstract readComparative Study
In one paragraph
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 506 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
506citing papers in PubMed, 2 pooled it
49.2field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
506 citing papers in PubMed, 2 syntheses or guidelines pooled it, 793 citations in OpenAlex.
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- Integration of cell-specific gene expression and chromatin accessibility facilitates localization of neurodegenerative risk in microglia.bioRxiv : the preprint server for biology · 2026Article
- Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Selective collateralization of transcriptomically distinct neurons organizes visual-stream output from the primary visual cortex.bioRxiv : the preprint server for biology · 2026Article
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- A framework for comparative analysis of human and mouse cortical neuron dendrites in corresponding brain regions.Nature neuroscience · 2026Article
- Multiomic single-nucleus profiling reveals cell-type-specific epigenetic and transcriptional dysregulation in major depressive disorder brain.The international journal of neuropsychopharmacology · 2026Article
- Functional development of midbrain and pons during human gestation and electrophysiological markers for DS intervention.Journal of advanced research · 2026Article
- Systematic comparison of estimates of transcription factor activity by ATAC-seq and multiplexed reporter assays.Molecular systems biology · 2026Article
- Regional specialization of upper-layer inhibitory interneuron organization in the human prefrontal cortex.Journal of anatomy · 2026Article
- Primate neurons with special signalling logic.Nature cell biology · 2026Article
446 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
106 authors at 17 institutions in 3 countries.
Trygve E BakkenAllen Institute for Brain Science, Seattle, WA, USA. trygveb@alleninstitute.org.ORCID http://orcid.org/0000-0003-3373-7386
Nikolas L JorstadAllen Institute for Brain Science, Seattle, WA, USA.
Qiwen HuDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Blue B LakeDepartment of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Wei TianThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Brian E KalmbachAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-3136-8097
Megan CrowStanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.ORCID http://orcid.org/0000-0002-1172-5897
Rebecca D HodgeAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-5784-9668
Fenna M KrienenDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-1400-6820
Staci A SorensenAllen Institute for Brain Science, Seattle, WA, USA.
Jeroen EggermontLKEB, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Zizhen YaoAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-9361-5607
Brian D AevermannJ. Craig Venter Institute, La Jolla, CA, USA.
Andrew I AldridgeGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-1962-8802
Anna BartlettGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Darren BertagnolliAllen Institute for Brain Science, Seattle, WA, USA.
Tamara CasperAllen Institute for Brain Science, Seattle, WA, USA.
Rosa G CastanonGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Kirsten CrichtonAllen Institute for Brain Science, Seattle, WA, USA.
Tanya L DaigleAllen Institute for Brain Science, Seattle, WA, USA.
Rachel DalleyAllen Institute for Brain Science, Seattle, WA, USA.
Nick DeeAllen Institute for Brain Science, Seattle, WA, USA.
Nikolai DembrowDepartment of Physiology and Biophysics, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-7699-6591
Dinh DiepDepartment of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Song-Lin DingAllen Institute for Brain Science, Seattle, WA, USA.
Weixiu DongDepartment of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Rongxin FangBioinformatics and Systems Biology Graduate Program, University of California, San Diego, La Jolla, CA, USA.
Stephan FischerStanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Melissa GoldmanDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Jeff GoldyAllen Institute for Brain Science, Seattle, WA, USA.
Lucas T GraybuckAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-8814-6818
Brian R HerbInstitute for Genomes Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
Xiaomeng HouCenter for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
Jayaram KancherlaDepartment of Computer Science, University of Maryland College Park, College Park, MD, USA.
Matthew KrollAllen Institute for Brain Science, Seattle, WA, USA.
Kanan LathiaAllen Institute for Brain Science, Seattle, WA, USA.
Baldur van LewLKEB, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0003-0628-1264
Yang Eric LiCenter for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6997-6018
Christine S LiuSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Hanqing LiuGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Jacinta D LuceroThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Anup MahurkarInstitute for Genomes Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-4999-2296
Delissa McMillenAllen Institute for Brain Science, Seattle, WA, USA.
Jeremy A MillerAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-4549-588X
Marmar MoussaUniversity of Connecticut, Storrs, CT, USA.
Joseph R NeryGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-0153-5659
Philip R NicovichAllen Institute for Brain Science, Seattle, WA, USA.
Sheng-Yong NiuGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Joshua OrvisInstitute for Genomes Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
Julia K OsteenThe Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-7058-3297
Scott OwenAllen Institute for Brain Science, Seattle, WA, USA.
Carter R PalmerSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Thanh PhamAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-4738-5062
Nongluk PlongthongkumDepartment of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Olivier PoirionCenter for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
Nora M ReedDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Christine RimorinAllen Institute for Brain Science, Seattle, WA, USA.
Angeline RivkinThe Salk Institute for Biological Studies, La Jolla, CA, USA.
William J RomanowSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Adriana E Sedeño-CortésAllen Institute for Brain Science, Seattle, WA, USA.
Kimberly SilettiDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Saroja SomasundaramAllen Institute for Brain Science, Seattle, WA, USA.
Josef SulcAllen Institute for Brain Science, Seattle, WA, USA.
Michael TieuAllen Institute for Brain Science, Seattle, WA, USA.
Amy TorkelsonAllen Institute for Brain Science, Seattle, WA, USA.
Herman TungAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0812-3318
Xinxin WangMcDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USA.ORCID http://orcid.org/0000-0001-6393-2276
Fangming XieDepartment of Physics, University of California, San Diego, La Jolla, CA, USA.
Anna Marie YannyAllen Institute for Brain Science, Seattle, WA, USA.
Renee ZhangJ. Craig Venter Institute, La Jolla, CA, USA.
Seth A AmentInstitute for Genomes Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-6443-7509
M Margarita BehrensThe Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-7168-8186
Hector Corrada BravoDepartment of Computer Science, University of Maryland College Park, College Park, MD, USA.
Jerold ChunSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-3964-0921
Alexander DobinCold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Jesse GillisStanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Ronna HertzanoDepartments of Otorhinolaryngology, Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA.
Patrick R HofNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Thomas HölltComputer Graphics and Visualization Group, Delt University of Technology, Delft, The Netherlands.ORCID http://orcid.org/0000-0001-8125-1650
Gregory D HorwitzDepartment of Physiology and Biophysics, Washington National Primate Research Center, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-5130-5259
C Dirk KeeneDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-5291-1469
Peter V KharchenkoDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6036-5875
Andrew L KoDepartment of Neurological Surgery, University of Washington School of Medicine, Seattle, WA, USA.
Boudewijn P LelieveldtLKEB, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-8269-7603
Chongyuan LuoDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
Eran A MukamelDepartment of Cognitive Science, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-3203-9535
António Pinto-DuarteThe Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-2215-7653
Sebastian PreisslCenter for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-8971-5616
Aviv RegevBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-3293-3158
Bing RenCenter for Epigenomics, Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-5435-1127
Richard H ScheuermannJ. Craig Venter Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-1355-892X
Kimberly SmithAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-3142-1970
William J SpainDepartment of Physiology and Biophysics, University of Washington, Seattle, WA, USA.
Owen R WhiteInstitute for Genomes Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
Christof KochAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-6482-8067
Michael HawrylyczAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-5741-8024
Bosiljka TasicAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-6861-4506
Evan Z MacoskoBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-2794-5165
Steven A McCarrollDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6954-8184
Jonathan T TingAllen Institute for Brain Science, Seattle, WA, USA.
Hongkui ZengAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0326-5878
Kun ZhangDepartment of Bioengineering, University of California, San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-7596-5224
Guoping FengMcGovern Institute for Brain Research, MIT, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-8021-277X
Joseph R EckerGenomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-5799-5895
Sten LinnarssonDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-3491-3444
Ed S LeinAllen Institute for Brain Science, Seattle, WA, USA. edl@alleninstitute.org.ORCID http://orcid.org/0000-0001-9012-6552
Allen Institute for Brain Science · USSalk Institute for Biological Studies · USUniversity of California San Diego · USUniversity of Maryland, Baltimore · USHarvard University · USUniversity of Washington · USBroad Institute · USCold Spring Harbor Laboratory · USSanford Burnham Prebys Medical Discovery Institute · USJ. Craig Venter Institute · USLeiden University Medical Center · NLKarolinska Institutet · SEUniversity of Maryland, College Park · USDelft University of Technology · NLJames S. McDonnell Foundation · USUniversity of California, Los Angeles · USUniversity of Connecticut · US
Funding
Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8MGeneration of novel cell type specific mouse genetic toolsU19MH114830 · NIMH · ALLEN INSTITUTE · PI ANDERSON, DAVID J, PACHTER, LIOR S · 2017 to 2021
$64.7MTool and Technology Development CoreU19MH114821 · NIMH · COLD SPRING HARBOR LABORATORY · PI MITRA, PARTHA PRATIM · 2017 to 2021
$64.5MInstitute of Translational Health SciencesUL1TR000423 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$49.4MUniversity of Washington Alzheimer's Disease Research CenterP30AG066509 · NIA · UNIVERSITY OF WASHINGTON · PI Thomas J. Grabowski · 2020 to 2026
$29.0MMolecular SignaturesU19MH114831 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI CALLAWAY, EDWARD M · 2017 to 2021
$24.6MA multimodal atlas of human brain cell typesU01MH114812 · NIMH · ALLEN INSTITUTE · PI LEIN, ED · 2017 to 2021
$19.2MA BRAIN Initiative Resource: The Neuroscience Multi-omic Data ArchiveR24MH114788 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI Anup Mahurkar, Owen R White · 2017 to 2026
$17.2MToward a human adult brain cell atlas with single-cell technologiesU01MH114828 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHUN, JEROLD, REN, BING · 2018 to 2022
$8.7MA Molecular and Cellular Atlas of the Marmoset BrainU01MH114819 · NIMH · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI FENG, GUOPING · 2017 to 2021
$6.9MSlowly Inactivating K+ Channels in Pyramidal NeuronsR01NS044163 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI FOEHRING, ROBERT C, SPAIN, WILLIAM J · 2003 to 2022
$6.5MEpigenomic cell-type classification and regulatory element identification in the human brainU01MH121282 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI BEHRENS, M MARGARITA, ECKER, JOSEPH R · 2019 to 2021
$5.4MHoward Hughes Medical InstituteNCATS NIH HHS UL1 TR000423NHGRI NIH HHS R01 HG009318NIA NIH HHS P30 AG066509NIDA NIH HHS R01 DA036909NIDCD NIH HHS R01 DC019370NIDCD NIH HHS U01 DC013817NIH HHS P51 OD010425NIH HHS U01 MH114812-02NIMH NIH HHS R24 MH114788NIMH NIH HHS R24 MH114815NIMH NIH HHS RF1 MH114126NIMH NIH HHS RF1 MH123220NIMH NIH HHS U01 MH114812NIMH NIH HHS U01 MH114819NIMH NIH HHS U01 MH114828NIMH NIH HHS U01 MH121282NIMH NIH HHS U19 MH114821NIMH NIH HHS U19 MH114830NIMH NIH HHS U19 MH114831NINDS NIH HHS R01 NS044163
Abstract
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals
Indexed as
Single-Cell AnalysisAnimalsAtlases as TopicCallithrixEpigenesis, GeneticEpigenomicsFemaleGABAergic NeuronsGene Expression ProfilingGlutamatesHumansIn Situ Hybridization, FluorescenceMaleMiceMiddle AgedMotor CortexGlutamates
Identifiers
What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.