Evidence map›Paper›PMID 34615887›Full record

ArticleScientific reports2021

Molecular imaging of myogenic stem/progenitor cells with [

Weronika Wargocka-Matuszewska, Katarzyna Fiedorowicz, Anna Rugowska, Karolina Bednarowicz, Agnieszka Zimna, Łukasz Cheda, Paulina Hamankiewicz, Krzysztof Kilian, Michał Fiedorowicz, Monika Drabik and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. [Advances in multimodal biomedical imaging of small animals].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Weronika Wargocka-MatuszewskaFaculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Żwirki i Wigury 101, 02-089, Warsaw, Poland.
Katarzyna FiedorowiczInstitute of Human Genetics Polish Academy of Science, Strzeszyńska 32, 60-479, Poznan, Poland.
Anna RugowskaInstitute of Human Biology and Evolution, Faculty of Biology Adam, Mickiewicz University, Uniwersytetu Poznańskiego 6, 61-614, Poznan, Poland.
Karolina BednarowiczInstitute of Human Genetics Polish Academy of Science, Strzeszyńska 32, 60-479, Poznan, Poland.
Agnieszka ZimnaInstitute of Human Genetics Polish Academy of Science, Strzeszyńska 32, 60-479, Poznan, Poland.
Łukasz ChedaFaculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Żwirki i Wigury 101, 02-089, Warsaw, Poland.
Paulina HamankiewiczFaculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Żwirki i Wigury 101, 02-089, Warsaw, Poland.
Krzysztof KilianHeavy Ion Laboratory, University of Warsaw, Pasteura 5A, 02-093, Warsaw, Poland.
Michał FiedorowiczMossakowski Medical Research Centre Polish Academy of Science, Pawińskiego 5, 02-106, Warsaw, Poland.
Monika DrabikMossakowski Medical Research Centre Polish Academy of Science, Pawińskiego 5, 02-106, Warsaw, Poland.
Natalia RozwadowskaInstitute of Human Genetics Polish Academy of Science, Strzeszyńska 32, 60-479, Poznan, Poland.
Zbigniew RogulskiFaculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Żwirki i Wigury 101, 02-089, Warsaw, Poland. rogul@chem.uw.edu.pl.ORCID 0000-0002-2372-850X
Maciej KurpiszInstitute of Human Genetics Polish Academy of Science, Strzeszyńska 32, 60-479, Poznan, Poland. maciej.kurpisz@igcz.poznan.pl.ORCID 0000-0003-3275-3245
Institute of Human Genetics · PLUniversity of Warsaw · PLMossakowski Medical Research Institute, Polish Academy of Sciences · PLAdam Mickiewicz University in Poznań · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preclinical and clinical studies have shown that stem cells can promote the regeneration of damaged tissues, but therapeutic protocols need better quality control to confirm the location and number of transplanted cells. This study describes in vivo imaging while assessing reporter gene expression by its binding to a radiolabelled molecule to the respective receptor expressed in target cells. Five mice underwent human skeletal muscle-derived stem/progenitor cell (huSkMDS/PC EF1-HSV-TK) intracardial transplantation after induction of myocardial infarction (MI). The metabolic parameters of control and post-infarction stem progenitor cell-implanted mice were monitored using 2-deoxy-18F-fluorodeoxyglucose ([

Indexed as

Fluorodeoxyglucose F18Molecular ImagingPositron Emission Tomography Computed TomographyAdult Stem CellsAnimalsDisease Models, AnimalEchocardiographyFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiceMice, SCIDMyoblasts, CardiacMyocardial InfarctionFluorodeoxyglucose F18poly(3-hydroxybutyrate)-co-(3-hydroxyvalerate)PolyestersPolyhydroxybutyrates

Identifiers

PMID34615887
PMCPMC8494811
OpenAlexW3184871246

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.