ReviewEuropean respiratory review : an official journal of the European Respiratory Society2021
Thoracic involvement and imaging patterns in IgG4-related disease.
Review in European respiratory review : an official journal of the European Respiratory Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Pulmonary manifestations, treatments and outcomes of IgG4-related disease-a systematic literature review.Rheumatology international · 2024Pooled it
- Nodular Pulmonary Sarcoidosis with a B-cell Reaction Similar to That of IgG4-related Disease.Internal medicine (Tokyo, Japan) · 2026Article
- Isolated pulmonary and renal IgG4-related disease: a rare dual-organ presentation diagnosed via video-assisted thoracoscopic surgery.BMJ case reports · 2026Article
- CT Chest findings in IgG4-related disease.Annals of medicine · 2025Article
- Clinical characteristics of IgG4-related lung disease: a single-center based experience.Clinical rheumatology · 2025Article
- Comments and Illustrations of the European Federation of Societies for Ultrasound in Medicine Guidelines: Benign Pleura Lesions (Benign Pleura Thickening, Lesions and Masses)-What Can Be Seen on Transthoracic Ultrasound?Diagnostics (Basel, Switzerland) · 2025Review
- Coronary periarteritis and pericarditis are rare but distinct manifestations of heart involvement in IgG4-related disease: a retrospective cohort study.Orphanet journal of rare diseases · 2024Article
- Immunoglobulin G4-related thoracic disease: clinical and radiological findings of a Turkish cohort.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024Article
- The development and initial validation of IgG4-related disease damage index: a consensus report from Chinese IgG4-RD Consortium.RMD open · 2024Article
- Thoracic manifestations of IgG4-related disease.Respirology (Carlton, Vic.) · 2023Review
- Clinical characteristics of IgG4Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Article
- IgG4-related diseases involving pleura: a case report and literature review.Frontiers in medicine · 2023Article
- Large lung mass lesion with spontaneous regression in a patient with IgG4-related lung disease.Respirology case reports · 2023Article
- Pulmonary IgG4-related disease with favourable response to rituximab: A case report.Respirology case reports · 2022Article
- IgG4 related lung disease mimicking multiple pleural disseminated lung cancer.Respirology case reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveImmunoglobulin G4-related disease (IgG4-RD) is a rare orphan disease. Lung, pleura, pericardium, mediastinum, aorta and lymph node involvement has been reported with variable frequency and mostly in Asian studies. The objective of this study was to describe thoracic involvement assessed by high-resolution thoracic computed tomography (CT) in Caucasian patients with IgG4-RD.
methodsThoracic CT scans before treatment were retrospectively collected through the French case registry of IgG4-RD and a single tertiary referral centre. CT scans were reviewed by two experts in thoracic imagery blinded from clinical data.
results48 IgG4-RD patients with thoracic involvement were analysed. All had American College of Rheumatology/European League Against Rheumatism classification scores ≥20 and comprehensive diagnostic criteria for IgG4-RD. CT scan findings showed heterogeneous lesions. Seven patterns were observed: peribronchovascular involvement (56%), lymph node enlargement (31%), nodular disease (25%), interstitial disease (25%), ground-glass opacities (10%), pleural disease (8%) and retromediastinal fibrosis (4%). In 37% of cases two or more patterns were associated. Asthma was significantly associated with peribronchovascular involvement (p=0.04). Among eight patients evaluated by CT scan before and after treatments, only two patients with interstitial disease displayed no improvement.
conclusionThoracic involvement of IgG4-RD is heterogeneous and likely underestimated. The main thoracic CT scan patterns are peribronchovascular thickening and thoracic lymph nodes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.