Evidence map›Paper›PMID 34615672›Full record

ArticleBMJ open2021

Dementia and disadvantage in the USA and England: population-based comparative study.

Karolos Arapakis, Eric Brunner, Eric French, Jeremy McCauley

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Inequalities in the burden of disease due to dementia, including Alzheimer disease, in British Columbia, Canada, from 2001 to 2022.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Predictors of falls in older adults with and without dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  13. Examining the Impact of Socioeconomic Position Across the Life Course on Cognitive Function and Brain Structure in Healthy Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  14. Article
  15. How should we fund end-of-life care in the US?Lancet regional health. Americas · 2022
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karolos ArapakisDepartment of Economics, UCL, London, UK.ORCID 0000-0001-5690-5472
Eric BrunnerDepartment of Epidemiology and Public Health, University College London, London, UK.ORCID 0000-0002-0595-4474
Eric FrenchDepartment of Economics, Cambridge University, Cambridge, UK.
Jeremy McCauleySchool of Economics, University of Bristol, Bristol, UK jeremy.mccauley@bristol.ac.uk.ORCID 0000-0002-8402-483X

Funding

British Heart Foundation RG/13/2/30098British Heart Foundation RG/16/11/32334Medical Research Council MR/S011676/1
6 · The paper itself

Abstract

objectivesTo compare dementia prevalence and how it varies by socioeconomic status (SES) across the USA and England.

designPopulation-based comparative study.

settingNon-Hispanic whites aged over 70 population in the USA and England.

participantsData from the Health and Retirement Study and the English Longitudinal Study of Ageing, which are harmonised, nationally representative panel studies. The sample includes 5330 and 3147 individuals in the USA and England, respectively.

main outcome measuresBetween country differences in age-gender standardised dementia prevalence, across the SES gradient. Dementia prevalence was estimated in each country using an algorithm based on an identical battery of demographic, cognitive and functional measures.

resultsDementia prevalence is higher among the disadvantaged in both countries, with the USA being more unequal according to four measures of SES. Overall prevalence was lower in England at 9.7% (95% CI 8.9% to 10.6%) than the USA at 11.2% (95% CI 10.6% to 11.8%), a difference of 1.4 percentage points (pp) (p=0.0055). Most of the between country difference is driven by the bottom of the SES distribution. In the lowest income decile individuals in the USA had 7.3 pp (p<0.0001) higher prevalence than in England. Once past health factors and education were controlled for, most of the within country inequalities disappeared; however, the cross-country difference in prevalence for those in lowest income decile remained disproportionately high.

conclusionsThere is inequality in dementia prevalence according to income, wealth and education in both the USA and England. England has lower dementia prevalence and a less steep SES gradient. Most of the cross-country difference is concentrated in the lowest SES group, which provides evidence that disadvantage in the USA is a disproportionately high risk factor for dementia.

Indexed as

DementiaIncomeAgedEducational StatusEnglandHumansLongitudinal StudiesPrevalenceSocial ClassSocioeconomic FactorsUnited Statesdementiahealth economicspublic health

Identifiers

PMID34615672
PMCPMC8496387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.