ReviewDeutsches Arzteblatt international2021
Scabies: Epidemiology, Diagnosis, and Treatment.
Review in Deutsches Arzteblatt international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Comparative effectiveness of ivermectin versus permethrin for the treatment of scabies: an updated systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- Global prevalence and predictors of scabies among prisoners: systematic review and meta-analysis.BMC public health · 2024Pooled it
- Risk factors for scabies in hospital: a systematic review.BMC infectious diseases · 2024Pooled it
- Anatomical Distribution of Scabies Lesions and Factors Associated With Typical Anatomical-Site Involvement Among Patients Attending a Dermatology Center in Mogadishu, Somalia: A Facility-Based Cross-Sectional Study.Health science reports · 2026Article
- Shotgun Metagenomic Characterization of Skin Microbiome Shifts in Human Scabies Before and After Scabicidal Treatment.International journal of molecular sciences · 2026Article
- A Case-Control Study of Risk Factors for Scabies Among Patients Attending Dermatology Clinics in Afghanistan.Health science reports · 2026Article
- Clinical characteristics associated with severe misdiagnosis of scabies: a retrospective hospital-based study.BMC infectious diseases · 2026Article
- Clinical features of 170 Chinese scabies cases and the therapeutic efficacy of sulfur ointment.PLoS neglected tropical diseases · 2026Article
- Integrated in vitro and in vivo evaluation of ivermectin hydrogel formulation for management of scabies with pharmacological assessment.Scientific reports · 2026Article
- Factors associated with scabies severity and reinfection: A cross-sectional study during recent surges in the Chattogram Division, Bangladesh.IJID regions · 2026Article
- Crusted scabies in an immunocompetent patient.Dermatology online journal · 2026Article
- Scabies among Dutch higher education students: do cases notify their contacts and do contacts take adequate measures?Parasites & vectors · 2026Article
- A novel rapid detection approach based on CRISPR-Cas13a for Dermatophagoides pteronyssinus and Dermatophagoides farinae (Acariformes: Pyroglyphidae).Journal of insect science (Online) · 2026Article
- From urticaria to mites: a diagnostic turnaround in atypical nodular scabies -a case report.BMC infectious diseases · 2026Article
- Ectoparasite- and Vector-Borne-Related Dermatoses: A Single-Centre Study with Practical Diagnostic and Management Insights in a One Health Perspective.Journal of clinical medicine · 2026Article
- Infantile scabies mimicking refractory eczema: a case report and review of the literature.Frontiers in medicine · 2026Article
- Including patient experiences from online sources in guidelines: A natural language processing study on scabies.PloS one · 2026Article
- Scabies Treatment Failure: Beyond Drug Resistance and Toward a Multidimensional Understanding.Journal of tropical medicine · 2026Review
- Rising scabies incidence and the growing burden on GPs: a retrospective longitudinal study.BJGP open · 2025Article
- Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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- Commented on byIn Reply.2022
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundScabies is a skin infestation whose incidence is apparently rising.
methodsThis review is based on pertinent articles retrieved by a selective search of PubMed on diagnosis and treatment strategies.
resultsThread-like papules (burrows), new, intense pruritus, and dermatitis guide the suspected diagnosis which is confirmed by the microscopic or dermatoscopic demonstration of scabies mites. The first line therapy is topical application of permethrin, in accordance with the current recommendations for its use. Other treatment options include systemic ivermectin and topical crotamiton or benzyl benzoate. A combination of permethrin and ivermectin is used to treat otherwise intractable cases and is generally indicated for the treatment of crusted scabies. Known causes of treatment failure include improper application of the external agents, failure of repeated treatment with ivermectin, incomplete decontamination of furnishings and clothes, failure to simultaneously treat contact persons, absence of written documents explaining treatment modalities, and the patient's belonging to a risk group. Even though there has not yet been any direct proof of resistance of scabies mites to permethrin, there is a rising number of welldocumented cases of poor response to this agent. Moxidectin is a new substance now undergoing clinical testing.
conclusionTreatment of scabies according to the guidelines and the additional recommendations reported here should result in effective curing, even in cases that are thought to be intractable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.