Evidence map›Paper›PMID 34615515›Full record

ArticleBMC public health2021

Identification of optimal thalassemia screening strategies for migrant populations in Thailand using a qualitative approach.

Julia Z Xu, Meghan Foe, Wilaslak Tanongsaksakul, Thidarat Suksangpleng, Supachai Ekwattanakit, Suchada Riolueang, Marilyn J Telen, Bonnie N Kaiser, Vip Viprakasit

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Thalassaemia.Nature reviews. Disease primers · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Potential Use of MicroRNA Technology in Thalassemia Therapy.Journal of clinical medicine research · 2024
    Review
  8. Review
  9. A Systematic Scoping Review on Migrant Health Coverage in Thailand.Tropical medicine and infectious disease · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Julia Z XuDepartment of Medicine, Duke University, Durham, USA. Julia.xu2@nih.gov.
Meghan FoeDepartment of Hematology/Oncology, University of California San Francisco Benioff Children's Hospital Oakland, Oakland, USA.
Wilaslak TanongsaksakulDepartment of Pediatrics, Laem Chabang Hospital, Laem Chabang, Thailand.
Thidarat SuksangplengSiriraj-Thalassemia Center, Mahidol University, Bangkok, Thailand.
Supachai EkwattanakitSiriraj-Thalassemia Center, Mahidol University, Bangkok, Thailand.
Suchada RiolueangSiriraj-Thalassemia Center, Mahidol University, Bangkok, Thailand.
Marilyn J TelenDepartment of Medicine, Duke University, Durham, USA.
Bonnie N KaiserDuke Global Health Institute, Duke University, Durham, USA.
Vip ViprakasitSiriraj-Thalassemia Center, Mahidol University, Bangkok, Thailand. vip.vip@mahidol.edu.
Duke University · USSiriraj Hospital · THMahidol University · THUCSF Benioff Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThalassemia is a common inherited hemoglobin disorder in Southeast Asia. Severe thalassemia can lead to significant morbidity for patients and economic strain for under-resourced health systems. Thailand's thalassemia prevention and control program has successfully utilized prenatal screening and diagnosis to reduce the incidence of severe thalassemia in Thai populations, but migrant populations are excluded despite having high thalassemia prevalence. We sought to identify key barriers to and facilitators of thalassemia screening and to develop tailored recommendations for providing migrants with access to thalassemia prevention and control.

methodsWe conducted 28 in-depth interviews and 4 focus group discussions (FGDs) in Chonburi, Thailand with Myanmar and Cambodian migrants, Thai healthcare providers, Thai parents of children affected by thalassemia, and migrant agents.

resultsParticipant narratives revealed that migrants' lack of knowledge about the prevalence, manifestations, severity, and inherited nature of thalassemia led to misconceptions, fear, or indifference toward thalassemia and screening. Negative perceptions of pregnancy termination were based in religious beliefs but compounded by other sociocultural factors, presenting a key obstacle to migrant uptake of prenatal screening. Additionally, structural barriers included legal status, competing work demands, lack of health insurance, and language barriers. Participants recommended delivering public thalassemia education in migrants' native languages, implementing carrier screening, and offering thalassemia screening in convenient settings.

conclusionsAn effective thalassemia prevention and control program should offer migrants targeted thalassemia education and outreach, universal coverage for thalassemia screening and prenatal care, and options for carrier screening, providing a comprehensive strategy for reducing the incidence of severe thalassemia in Thailand and establishing an inclusive model for regional thalassemia prevention and control.

Indexed as

Transients and MigrantsChildHealth Services AccessibilityHumansMass ScreeningThailandUniversal Health InsuranceBarriers to careGenetic testingHealthcare accessMigrantsMigration policyPrenatal screeningSoutheast AsiaTermination of pregnancyThailandThalassemia

Identifiers

PMID34615515
PMCPMC8495975
OpenAlexW3204253049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.