ArticleBMC plant biology2021
ZmCCT regulates photoperiod-dependent flowering and response to stresses in maize.
Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 42 citations in OpenAlex.
- Phenomics-derived temporal maize health and environmental index enhance physiology-informed genomic prediction of yield across environments.Plant physiology · 2026Article
- Molecular Crosstalk Between Flowering Time and Drought Adaptation in Cereal Crops.Plants (Basel, Switzerland) · 2026Review
- The ZmCOP1s-ZmCOL3 Module Enhances Late Flowering, Grain Yield and Grain Quality in Maize.Plant biotechnology journal · 2026Article
- Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Dissecting the genetic basis of agronomic traits by multi-trait GWAS and genetic networks in maize (aBIOTECH · 2025Article
- Progressive Water Deficit Impairs Soybean Growth, Alters Metabolic Profiles, and Decreases Photosynthetic Efficiency.Plants (Basel, Switzerland) · 2025Article
- Transcriptomic analysis revealed that short-day treatment of seedlings promotes flowering in maize (Zea mays L.).Genes & genomics · 2025Article
- ZmPRR37-ZmYSL14 module enhances salt stress tolerance in maize.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Historic rewiring of grass flowering time pathways and implications for crop improvement under climate change.The New phytologist · 2025Review
- Natural variation of CTB5 confers cold adaptation in plateau japonica rice.Nature communications · 2025Article
- OfWRKY17-OfC3H49 module responding to high ambient temperature delays flowering via inhibitingHorticulture research · 2025Article
- Article
- Studies on Candidate Genes Related to Flowering Time in a Multiparent Population of Maize Derived from Tropical and Temperate Germplasm.Plants (Basel, Switzerland) · 2024Article
- Molecular Links between Flowering and Abiotic Stress Response: A Focus onPlants (Basel, Switzerland) · 2023Review
- Identification of QTNs, QTN-by-environment interactions for plant height and ear height in maize multi-environment GWAS.Frontiers in plant science · 2023Article
- Article
- Linkage mapping combined with GWAS revealed the genetic structural relationship and candidate genes of maize flowering time-related traits.BMC plant biology · 2022Article
- Genome-wide identification of HD-ZIP transcription factors in maize and their regulatory roles in promoting drought tolerance.Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Multi-Omics Analysis Reveals a Regulatory Network of ZmCCT During Maize Resistance to Gibberella Stalk Rot at the Early Stage.Frontiers in plant science · 2022Article
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAppropriate flowering time is very important to the success of modern agriculture. Maize (Zea mays L.) is a major cereal crop, originated in tropical areas, with photoperiod sensitivity. Which is an important obstacle to the utilization of tropical/subtropical germplasm resources in temperate regions. However, the study on the regulation mechanism of photoperiod sensitivity of maize is still in the early stage. Although it has been previously reported that ZmCCT is involved in the photoperiod response and delays maize flowering time under long-day conditions, the underlying mechanism remains unclear.
resultsHere, we showed that ZmCCT overexpression delays flowering time and confers maize drought tolerance under LD conditions. Implementing the Gal4-LexA/UAS system identified that ZmCCT has a transcriptional inhibitory activity, while the yeast system showed that ZmCCT has a transcriptional activation activity. DAP-Seq analysis and EMSA indicated that ZmCCT mainly binds to promoters containing the novel motifs CAAAAATC and AAATGGTC. DAP-Seq and RNA-Seq analysis showed that ZmCCT could directly repress the expression of ZmPRR5 and ZmCOL9, and promote the expression of ZmRVE6 to delay flowering under long-day conditions. Moreover, we also demonstrated that ZmCCT directly binds to the promoters of ZmHY5, ZmMPK3, ZmVOZ1 and ZmARR16 and promotes the expression of ZmHY5 and ZmMPK3, but represses ZmVOZ1 and ZmARR16 to enhance stress resistance. Additionally, ZmCCT regulates a set of genes associated with plant development.
conclusionsZmCCT has dual functions in regulating maize flowering time and stress response under LD conditions. ZmCCT negatively regulates flowering time and enhances maize drought tolerance under LD conditions. ZmCCT represses most flowering time genes to delay flowering while promotes most stress response genes to enhance stress tolerance. Our data contribute to a comprehensive understanding of the regulatory mechanism of ZmCCT in controlling maize flowering time and stress response.
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