ArticleDrug and alcohol dependence2021
Use frequency and symptoms of nicotine dependence among adolescent E-cigarette users: Comparison of JUUL and Non-JUUL users.
Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 37 citations in OpenAlex.
- Joint effect of nicotine use and diabetes distress on glycemic control in young adults with type 1 diabetes.Journal of diabetes and its complications · 2025Trial
- Article
- Early Initiation and Dual Patterns of Cigarette and E-Cigarette Use among Adults in the Eastern Province, Saudi Arabia:Saudi medical journal · 2026Article
- What is the Addictive Potential from Vaping?Nordisk alkohol- & narkotikatidskrift : NAT · 2026Article
- Differences in AUTOS- and FTND-assessed dependence on various tobacco products among Chinese current tobacco/nicotine users.Scientific reports · 2026Article
- Understanding Reasons to Quit or Reduce Vaping and Associations With Quitting Outcomes Among High School Adolescents in Connecticut.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Article
- Chronic Pod-Mod E-Cigarette Aerosol Exposure Induces Aortic Dysfunction in Hypercholesterolemic Mice: Role of Oxidative Stress and Inflammation.Arteriosclerosis, thrombosis, and vascular biology · 2025Article
- Longitudinal patterns of e-cigarette use initiation and progression to frequent vaping from mid-to-late adolescence to young adulthood.Addiction (Abingdon, England) · 2025Article
- Article
- Health Care Provider E-Cigarette-Related Advice and E-Cigarette Harm Perceptions Among Youth.American journal of health promotion : AJHP · 2025Article
- Does the time to nicotine dependence vary by internalizing symptoms for young people who use e-cigarettes? An analysis of the Population Assessment of Tobacco and Health (PATH) study, (Waves 1-5; 2013-2019).Addictive behaviors · 2024Article
- Comparison of Indicators of Dependence for Vaping and Smoking: Trends Between 2017 and 2022 Among Youth in Canada, England, and the United States.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- Racial and Ethnic Disparities in Adolescent Combustible Tobacco Smoking From 2014 to 2020: Declines Are Lagging Among Non-Hispanic Black Youth.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- Reply to Foxon F. & Shiffman S. Regarding Comments on "Adjei et al. 2024 Symptoms of nicotine dependence by E-cigarette and cigarette use behavior and brand: A population-based, nationally representative cross-sectional study" [Drug Alcohol Depend. 255 (2024) 111059].Drug and alcohol dependence · 2024Article
- Symptoms of nicotine dependence by e-cigarette and cigarette use behavior and brand: A population-based, nationally representative cross-sectional study.Drug and alcohol dependence · 2024Article
- Non-combustible nicotine product cessation interventions in adolescents and young adults: A systematic review.Tobacco use insights · 2024Review
- Depressive symptoms prospectively increase risk for new onset cigarette and ENDS dependence symptoms.Addictive behaviors · 2024Article
- Strengths and Limitations of Web-Based Cessation Support for Individuals Who Smoke, Dual Use, or Vape: Qualitative Interview Study.JMIR formative research · 2023Article
- Development of Dependence in Smokers and Rodents With Voluntary Nicotine Intake: Similarities and Differences.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023Review
- Effects of dual use of e-cigarette and cannabis during adolescence on cigarette use in young adulthood.Tobacco control · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveNicotine exposure among adolescent e-cigarette users remains a public health concern. JUUL, a popular e-cigarette brand among youth, is particularly alarming given the high nicotine delivery (59 mg/mL). This study compares e-cigarette use frequency and symptoms of nicotine dependence among adolescent JUUL and non-JUUL users.
methodsWe analyzed data from the 2020 National Youth Tobacco Survey. Participants were n = 1713 U.S. middle and high school students who reported past 30-day e-cigarette use. We compared adolescent e-cigarette users who reported JUUL use to those who did not. Outcomes were: (1) symptoms of nicotine dependence (i.e. nicotine cravings; use within 30 min of waking); (2) past 30-day e-cigarette use frequency, categorized as 1-5 days, 6-19 days, and 20-30 days. Covariates were sex, race/ethnicity, other tobacco product use, primary e-cigarette device type (i.e., disposable; pod; mod/tank).
resultsOverall, 49.5% of adolescent e-cigarette users reported using JUUL in the past 30 days, 40.1% reported symptoms of nicotine dependence, and 36.2% reported using an e-cigarette on 20-30 days. JUUL users were 1.77 (95% CI: 1.36-2.31) times as likely to report symptoms of nicotine dependence and 1.43 (95% CI: 1.02-2.01) time as likely to report using e-cigarettes on 20-30 days, compared to 1-5 days, relative to non-JUUL users, controlling for covariates.
conclusionJUUL use was associated with greater odds of nicotine dependence and more frequent e-cigarette use among adolescents. Greater prevention and regulatory efforts should be made to prevent adolescent use of high dose nicotine devices such as JUUL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.