Evidence map›Paper›PMID 34614260›Full record

ReviewActa paediatrica (Oslo, Norway : 1992)2022

Providing children with COVID-19 vaccinations is challenging due to lack of data and wide-ranging parental acceptance.

Jiatong She, Lanqin Liu, Wenjun Liu

Abstract readReview
In one paragraph

Review in Acta paediatrica (Oslo, Norway : 1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiatong SheDepartment of Pediatrics, Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0000-0002-2474-2709
Lanqin LiuDepartment of Pediatrics, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0000-0001-8379-6240
Wenjun LiuDepartment of Pediatrics, Southwest Medical University, Luzhou, Sichuan, China.ORCID https://orcid.org/0000-0002-7205-0598

Funding

2020 University-level College Students' Innovative Entrepreneurial Training Plan Program NO.2020023Major Science and Technology Projects in Sichuan Province NO.2019YFS0531
6 · The paper itself

Abstract

aimVaccines are vital to ending the COVID-19 pandemic and we reviewed the data on vaccinating children, and including them in clinical trials, as most of the activity has focused on adults.

methodsEnglish and Chinese databases, including PubMed, Elsevier Scopus, Web of Science, CNKI and CQVIP were searched, along with websites such as the World Health Organization and the University of Oxford.

resultsWe identified 44 papers and 16 news items about vaccinating children against the virus, published from 10 February 2020 to 14 July 2021. Child vaccination has been slow and only a few countries have included children in Phase II or III clinical trials. The data on children were much more limited than on adults, but most children were asymptomatic or had mild symptoms and some deaths had been recorded. More clinical trials are needed to assess the safety and efficacy of vaccinating children, as higher vaccination levels can help to build up herd immunity. The percentage of parents willing to vaccinate their children against the virus ranged from 48.2% to 72.6%, with much lower rates for letting them participate in clinical trials.

conclusionVaccines should be offered to children as soon as their safety and efficacy are established.

Indexed as

COVID-19COVID-19 VaccinesAdultChildHumansPandemicsParentsSARS-CoV-2VaccinationCOVID-19 Vaccinesefficacyherd immunityparentssafetyvaccine

Identifiers

PMID34614260
PMCPMC8653137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.