ArticleDevelopmental medicine and child neurology2022
Muscle synergy structure and gait patterns in children with spastic cerebral palsy.
Article in Developmental medicine and child neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of Functional Electrical Stimulation on Gait Parameters in Children with Cerebral Palsy: A Meta-Analysis.Computational and mathematical methods in medicine · 2022Pooled it
- Activation Duty Cycle and Regional Muscle Co-Activation Across GMFCS Levels in Ambulatory Children with Spastic Cerebral Palsy: An Exploratory Surface EMG Study.Sensors (Basel, Switzerland) · 2026Article
- Influence of surgical intervention on pre- and post-surgery patient specific muscle synergies in children with cerebral palsy.Experimental brain research · 2026Article
- Impact of an occupational back-support exoskeleton on muscle synergies during a pick-up movement.European journal of applied physiology · 2026Article
- Task complexity amplifies spatial asymmetry of muscle synergy plasticity in chronic stroke survivors.Journal of neuroengineering and rehabilitation · 2026Article
- The role of independent walking in the maturation of the spinal locomotor output in children with cerebral palsy.Frontiers in physiology · 2026Article
- Enhancing Jump Performance Through Blood Flow Restriction Squat Exercise: A Muscle Synergy Analysis Using Wavelet Packet Transformation.Journal of sports science & medicine · 2025Article
- Higher involvement of synergistic muscle than active muscles in ankle plantar flexion.Scientific reports · 2025Article
- The Gait Pattern Classification System for Children with Spastic Cerebral Palsy (GaP-CP)-A Validity Study.Children (Basel, Switzerland) · 2025Article
- Can muscle synergies shed light on the mechanisms underlying motor gains in response to robot-assisted gait training in children with cerebral palsy?Journal of neuroengineering and rehabilitation · 2025Article
- Correlation analysis of upper limb muscle activation in the frequency domain in wheelchair fencers.Frontiers in human neuroscience · 2025Article
- Characterization of muscle synergy similarity and adaptation in hip exoskeleton-assisted locomotion.Frontiers in bioengineering and biotechnology · 2025Article
- Kinematic-Muscular Synergies Describe Human Locomotion with a Set of Functional Synergies.Biomimetics (Basel, Switzerland) · 2024Article
- Comparison of the forward and sideways locomotor patterns in children with Cerebral Palsy.Scientific reports · 2023Article
- Variability of trunk muscle synergies underlying the multidirectional movements and stability trunk motor tasks in healthy individuals.Scientific reports · 2023Article
- Recent developments in muscle synergy analysis in young people with neurodevelopmental diseases: A Systematic Review.Frontiers in bioengineering and biotechnology · 2023Review
- Computational prediction of muscle synergy using a finite element framework for a musculoskeletal model on lower limb.Frontiers in bioengineering and biotechnology · 2023Article
- A longitudinal analysis of selective motor control during gait in individuals with cerebral palsy and the relation to gait deviations.PloS one · 2023Article
- Development of running is not related to time since onset of independent walking, a longitudinal case study.Frontiers in human neuroscience · 2023Article
- Evaluation of Spatiotemporal Patterns of the Spinal Muscle Coordination Output during Walking in the Exoskeleton.Sensors (Basel, Switzerland) · 2022Article
Corrections and comments
- Commented on by
Authors and funding
9 authors.
Funding
Abstract
aimTo determine if muscle synergy structure (activations and weights) differs between gait patterns in children with spastic cerebral palsy (CP).
methodIn this cross-sectional study, we classified 188 children with unilateral (n=82) or bilateral (n=106) spastic CP (mean age: 9y 5mo, SD: 4y 3mo, range: 3y 9mo-17y 7mo; 75 females; Gross Motor Function Classification System [GMFCS] level I: 106, GMFCS level II: 55, GMFCS level III: 27) into a minor deviations (n=34), drop foot (n=16), genu recurvatum (n=26), apparent equinus (n=53), crouch (n=39), and jump gait pattern (n=20). Surface electromyography recordings from eight lower limb muscles of the most affected side were used to calculate synergies with weighted non-negative matrix factorization. We compared synergy activations and weights between the patterns.
resultsSynergy structure was similar between gait patterns, although weights differed in the more impaired children (crouch and jump gait) when compared to the other patterns. Variability in synergy structure between participants was high.
interpretationThe similarity in synergy structure between gait patterns suggests a generic motor control strategy to compensate for the brain lesion. However, the differences in weights and high variability between participants indicate that this generic motor control strategy might be individualized and dependent on impairment level.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.