ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2021
Early neonatal sepsis: prevalence, complications and outcomes in newborns with 35 weeks of gestational age or more.
Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Presepsin as a diagnostic biomarker for sepsis across neonates, children, and adults: A meta-analysis.Biomolecules & biomedicine · 2025Pooled it
- On the usage of artificial intelligence for identifying main attributes and predicting neonatal sepsis.Scientific reports · 2026Article
- 16 S rRNA-based molecular identification of coagulase-negative Staphylococcus species in neonates with sepsis and their antibiotic resistance patterns in Ahvaz, Iran.BMC microbiology · 2025Article
- Implementation of an EOS calculator-based protocol decreased infant antibiotic exposure in chorioamnionitis without correlation with placental histopathology.Journal of perinatology : official journal of the California Perinatal Association · 2025Observational
- EMX2OS serves as a biomarker of neonatal sepsis and participates acute lung injury through enhancing ferroptosis.Frontiers in pediatrics · 2025Article
- Crossing Age Boundaries: The Unifying Potential of Presepsin in Sepsis Diagnosis Across Diverse Age Groups.Journal of clinical medicine · 2024Review
- AI Algorithms for Modeling the Risk, Progression, and Treatment of Sepsis, Including Early-Onset Sepsis-A Systematic Review.Journal of clinical medicine · 2024Review
- Article
- Early-onset neonatal sepsis as a risk factor for peri-intraventricular hemorrhage in premature infants.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2024Article
- Exploring the use of cluster analysis to assess antibiotic stewardship in critically-ill neonates in a low resource setting.Antimicrobial resistance and infection control · 2023Article
- An Analysis of Predictive Factors for Severe Neonatal Infection and the Construction of a Prediction Model.Infection and drug resistance · 2023Article
- Incidence Rate and Associated Factors of Early Onset Sepsis Among Neonate Born at ≥35 Weeks' Gestation in Thai Tertiary Hospital.Infection and drug resistance · 2023Article
- Early-Onset Neonatal Sepsis in Low- and Middle-Income Countries: Current Challenges and Future Opportunities.Infection and drug resistance · 2022Review
- Conservative management of newborns with 35 weeks or more of gestational age at risk for early-onset sepsis: a Brazilian cohort study.Jornal de pediatriaArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyze the incidence, complications, and hospital discharge status in newborns with ≥35 weeks of gestational age with early neonatal sepsis.
methodsThis is a cross-sectional, retrospective study. Cases of early-onset sepsis registered from January 2016 to December 2019 in neonates with gestational age of 35 weeks or more were reviewed in a level III neonatal unit. The diagnoses were performed based on the criteria by the Brazilian Health Regulatory Agency (Anvisa), and the episodes were classified according to microbiological classification and site of infection. The following complications were evaluated: shock, coagulation disorders, and sequelae of the central nervous system. The conditions at hospital discharge were also assessed. The collected data were analyzed with the descriptive analysis.
resultsIn the period, early neonatal sepsis occurred in 46 newborns, corresponding to 1.8% of all newborns admitted to the neonatal unit, with a prevalence of 4/1,000 live births. Culture confirmed sepsis ocurred in three patients (0.3/1,000 live births), with the following agents: S. pneumoniae, S. epidermidis and S. agalactiae. As to site of infection, there were 35 cases of primary bloodstream infection, seven cases of pneumonia and four cases of meningitis. Most patients (78.3%) had at least one risk factor for sepsis, and all were symptomatic at admission. There were no deaths. Complications occurred in 28.2% of the cases, especially shock (10 cases - 21.7%).
conclusionsThe prevalence of proven early neonatal sepsis was low. Despite the common occurrence of complications, there were no deaths.
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