Evidence map›Paper›PMID 34614131›Full record

ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2021

Congenital anomalies in Santa Catarina: case distribution and trends in 2010-2018.

Bruna Muraro Vanassi, Gabriel Cremona Parma, Vivyane Santiago Magalhaes, Augusto César Cardoso Dos Santos, Betine Pinto Moehlecke Iser

Open access · diamondAbstract read
In one paragraph

Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Observational
  3. Prevalence of congenital anomalies in newborns: a cross-sectional study in the state of Rio de Janeiro, Brazil, 2019-2021.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Bruna Muraro VanassiUniversidade do Sul de Santa Catarina, Tubarão, SC, Brazil.ORCID http://orcid.org/0000-0002-7439-2399
Gabriel Cremona ParmaUniversidade do Sul de Santa Catarina, Tubarão, SC, Brazil.ORCID http://orcid.org/0000-0001-9540-6908
Vivyane Santiago MagalhaesSecretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, DF, Brazil.ORCID http://orcid.org/0000-0002-9540-4619
Augusto César Cardoso Dos SantosSecretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, DF, Brazil.ORCID http://orcid.org/0000-0002-1499-9105
Betine Pinto Moehlecke IserUniversidade do Sul de Santa Catarina, Tubarão, SC, Brazil.ORCID http://orcid.org/0000-0001-6061-2541
Universidade do Sul de Santa Catarina · BRSecretaria da Saúde · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the distribution of cases of congenital anomalies in the state of Santa Catarina by health macro-region, to determine the frequency according to maternal and neonatal variables, to estimate the related mortality, and the trends in the period 2010-2018.

methodsAn ecological time-series study with secondary data on congenital anomalies and the sociodemographic and health variables of mothers and newborns living in Santa Catarina, from 2010 to 2018. For temporal trend analysis, generalized linear regression was performed using the Prais-Winsten method with robust variance.

resultsThe average prevalence of congenital anomalies in the period was 8.9 cases per 1,000 live births, being 9.4 cases by 1,000 live births in 2010 and, in 2018, 8.2/1,000. The trend remained stable in the analyzed period. The major malformations were musculoskeletal, hip, and foot malformations, with a proportion ≥30%. There was a higher prevalence of congenital anomalies in low birthweight, preterm, male livebirths with Apgar≤7, born by cesarean section, mothers of older age (≥40 years), and less educated (less than eight years of study). Infant mortality due to congenital malformations was 2.6 deaths/1,000 live births, representing about 25.8% of the total infant deaths in the period.

conclusionsThe frequency of congenital anomalies and the mortality with anomalies was stable in the studied period in Santa Catarina. The presence of anomalies was associated with low birth weight, prematurity, and low Apgar score. The highest proportion of congenital anomalies was in the musculoskeletal system.

Indexed as

Congenital AbnormalitiesInfant, Premature, DiseasesAgedCesarean SectionFemaleHumansInfantInfant MortalityInfant, NewbornLive BirthMalePregnancyPrevalence

Identifiers

PMID34614131
PMCPMC8543791
OpenAlexW3201668364

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.