Evidence map›Paper›PMID 34613826›Full record

ArticleJournal of the International Association of Providers of AIDS Care

Presentation, Clinical Characteristics, and Treatment Outcomes among Tuberculous Meningitis Patients with and Without HIV Infection at Vajira Hospital, Thailand: A Retrospective Cohort Study.

Lakkana Boonyagars, Chunlanee Sangketchon, Kittisak Pholtawornkulchai

Open access · goldAbstract read
In one paragraph

Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Observational
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lakkana BoonyagarsDepartment of infectious diseases, Faculty of Medicine, Vajira Hospital, 292577Navamindradhiraj University, Bangkok, Thailand.ORCID 0000-0001-5010-6928
Chunlanee SangketchonDepartment of Disaster and Emergency Medical Operations, Faculty of Science and Health Technology, Vajira Hospital, 292577Navamindradhiraj University, Bangkok, Thailand.
Kittisak PholtawornkulchaiDepartment of infectious diseases, Faculty of Medicine, Vajira Hospital, 292577Navamindradhiraj University, Bangkok, Thailand.ORCID 0000-0002-5298-4553
Navamindradhiraj University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare the characteristics, presentation, investigations, and outcomes in tuberculous meningitis (TBM) patients with and without human immunodeficiency virus (HIV) coinfection. A retrospective cohort study was conducted on adult (age > 18 years) patients whose final diagnosis was TBM and who were treated at Vajira Hospital, Navamindradhiraj University, Thailand, between January 2005 and December 2016. A final total of 174 individuals were included in the study. Of these, 97 (55.75%) were HIV positive. Treatment was successful in 53 (30.5%) individuals. In HIV-infected TBM patients, there were higher proportions of patients who were younger in age (≤40 years), patients with a low body mass index, history of previous tuberculosis infection, or hepatitis C virus coinfection. A successful treatment outcome rate was lower in HIV-infected TBM patients than in HIV-uninfected TBM patients. Since HIV infection decreases the chance of successful treatment outcomes of TBM patients, future studies are needed to determine the clinical indicators for poorer survival outcomes in HIV-positive TBM patients.

Indexed as

HIV InfectionsTuberculosis, MeningealAdultHospitalsHumansMiddle AgedRetrospective StudiesThailandTreatment Outcomehuman immunodeficiency virusmycobacterial infectiontreatment outcometuberculous meningitis

Identifiers

PMID34613826
PMCPMC8725209
OpenAlexW3203730799

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.