ArticleJournal of virology2022
A QP509L/QP383R-Deleted African Swine Fever Virus Is Highly Attenuated in Swine but Does Not Confer Protection against Parental Virus Challenge.
Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 30 citations in OpenAlex.
- Hope and hurdles: unlocking the potential of modified live virus vaccines for African swine fever.Emerging microbes & infections · 2025Review
- An attenuated African swine fever virus with deletions of theJournal of virology · 2025Article
- Advances in African swine fever virus molecular biology and host interactions contributing to new tools for control.Journal of virology · 2025Review
- Strategic nucleic acid detection approaches for diagnosing African swine fever (ASF): navigating disease dynamics.Veterinary research · 2024Review
- Comprehensive Characterization of the Genetic Landscape of African Swine Fever Virus: Insights into Infection Dynamics, Immunomodulation, Virulence and Genes with Unknown Function.Animals : an open access journal from MDPI · 2024Review
- Article
- Identification and verification of the role of key metabolites and metabolic pathways on ASFV replication.iScience · 2024Article
- Recent progress on gene-deleted live-attenuated African swine fever virus vaccines.NPJ vaccines · 2024Review
- Recent progress and major gaps in the vaccine development for African swine fever.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Review
- Transcription termination and readthrough in African swine fever virus.Frontiers in immunology · 2024Article
- Identification ofFrontiers in microbiology · 2024Article
- Interactome between ASFV and host immune pathway proteins.mSystems · 2023Article
- Review
- Highly lethal genotype I and II recombinant African swine fever viruses detected in pigs.Nature communications · 2023Article
- Article
- SY18ΔL60L: a new recombinant live attenuated African swine fever virus with protection against homologous challenge.Frontiers in microbiology · 2023Article
- African swine fever virus QP383R dampens type I interferon production by promoting cGAS palmitoylation.Frontiers in immunology · 2023Article
- Vaccines for African swine fever: an update.Frontiers in microbiology · 2023Review
- Structure and function of African swine fever virus proteins: Current understanding.Frontiers in microbiology · 2023Review
- Comparative genomic and transcriptomic analyses of African swine fever virus strains.Computational and structural biotechnology journal · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
African swine fever (ASF), a devastating infectious disease in swine, severely threatens the global pig farming industry. Disease control has been hampered by the unavailability of vaccines. Here, we report that deletion of the QP509L and QP383R genes (ASFV-ΔQP509L/QP383R) from the highly virulent ASF virus (ASFV) CN/GS/2018 strain results in complete viral attenuation in swine. Animals inoculated with ASFV-ΔQP509L/QP383R at a 10
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Registered trials
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