Evidence map›Paper›PMID 34613773›Full record

ArticleScience advances2021

Junwei Zeng, Rajindra P Aryal, Kathrin Stavenhagen, Chi Luo, Renyan Liu, Xiaohui Wang, Jiaxuan Chen, Hao Li, Yasuyuki Matsumoto, Yingchun Wang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Distinct O-Linked Glycosylation Systems in Signaling and Immune Regulation.International journal of molecular sciences · 2026
    Review
  4. Article
  5. O-GalNAc glycans are enriched in neuronal tracts and regulate nodes of Ranvier.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Review
  8. GermlineProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Junwei ZengDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-8817-3744
Rajindra P AryalDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-8718-636X
Kathrin StavenhagenDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-9322-2945
Chi LuoDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
Renyan LiuDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Xiaohui WangDepartment of Developmental Biology, Harvard School of Dental Medicine, Boston, MA, USA.
Jiaxuan ChenDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-5801-9052
Hao LiDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-2171-8826
Yasuyuki MatsumotoDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Yingchun WangDepartment of Biochemistry, Emory University, Atlanta, GA, USA.
Jianmei WangDepartment of Biochemistry, Emory University, Atlanta, GA, USA.
Tongzhong JuDepartment of Biochemistry, Emory University, Atlanta, GA, USA.
Richard D CummingsDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-8918-5034
Beth Israel Deaconess Medical Center · USEmory University · USDana-Farber Cancer Institute · USHarvard University · US

Funding

Forging Translational Glycobiologists: Intermeshing Glycoscience Training and Clinical EducationK12HL141953 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAIKOF, ELLIOT, CUMMINGS, RICHARD D · 2018 to 2022
$4.8M
THE TUMOR ANTIGENS TN AND SIALYLTN IN HUMAN COLORECTAL CARCINOMAU01CA168930 · NCI · EMORY UNIVERSITY · PI CUMMINGS, RICHARD D, SMITH, DAVID FLETCHER · 2012 to 2016
$2.0M
NCI NIH HHS U01 CA168930NHLBI NIH HHS K12 HL141953
6 · The paper itself

Abstract

Factors regulating the induction and development of B cell–mediated autoimmunity are not well understood. Here, we report that targeted deletion in murine B cells of X-linked

Identifiers

PMID34613773
PMCPMC8494437
OpenAlexW3203979705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.