Evidence map›Paper›PMID 34613752›Full record

ArticleApplied and environmental microbiology2021

Florfenicol Enhances Colonization of a Salmonella enterica Serovar Enteritidis

Xueran Mei, Boheng Ma, Xiwen Zhai, Anyun Zhang, Changwei Lei, Lei Zuo, Xin Yang, Changyu Zhou, Hongning Wang

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Skin and gut microbiome in atopic dermatitis: Mechanisms and therapeutic opportunities.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  4. Cecal Metabolome Profiles of Turkey Poults in Response toAnimals : an open access journal from MDPI · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Virulence and Antimicrobial-Resistant Gene Profiles ofInternational journal of microbiology · 2024
    Article
  10. Review
  11. Article
  12. Review
  13. Prevalence and Characterization ofPathogens (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xueran Mei *Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan Universitygrid.13291.38, Chengdu, Sichuan, People's Republic of China.
Boheng Ma *Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan Universitygrid.13291.38, Chengdu, Sichuan, People's Republic of China.
Xiwen Zhai *Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan Universitygrid.13291.38, Chengdu, Sichuan, People's Republic of China.
Anyun ZhangKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan Universitygrid.13291.38, Chengdu, Sichuan, People's Republic of China.
Changwei LeiKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan Universitygrid.13291.38, Chengdu, Sichuan, People's Republic of China.
Lei ZuoKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan Universitygrid.13291.38, Chengdu, Sichuan, People's Republic of China.
Xin YangKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan Universitygrid.13291.38, Chengdu, Sichuan, People's Republic of China.
Changyu ZhouKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan Universitygrid.13291.38, Chengdu, Sichuan, People's Republic of China.
Hongning WangKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan Universitygrid.13291.38, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0002-7244-9929
Sichuan University · CNJinan University · CN

Funding

Agriculture Research System of China (China's Agricultural Research System) CARS-40-K14MOST | National Key Research and Development Program of China (NKRDPC) 2016YFD0501608National Natural Science Foundation of China (NSF) 3177131163National Natural Science Foundation of China (NSF) 31830098
6 · The paper itself

Abstract

Florfenicol is an important antibiotic commonly used in poultry production to prevent and treat Salmonella infection. However, oral administration of florfenicol may alter the animals' natural microbiota and metabolome, thereby reducing intestinal colonization resistance and increasing susceptibility to Salmonella infection. In this study, we determined the effect of florfenicol (30 mg/kg of body weight) on gut colonization of neonatal chickens challenged with Salmonella enterica subsp.

Indexed as

Gastrointestinal MicrobiomeMetabolomeAnimalsAnimals, NewbornAnti-Bacterial AgentsBacterial LoadChickensInflammationLinoleic AcidSalmonella enteritidisSalmonella Infections, AnimalThiamphenicolAnti-Bacterial AgentsflorfenicolLinoleic AcidThiamphenicolchickenflorfenicolgut microbiotametabolomeSalmonella

Identifiers

PMID34613752
PMCPMC8612288
OpenAlexW3204843054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.