Evidence map›Paper›PMID 34613605›Full record

ArticleJournal of microbiology (Seoul, Korea)2021

Antiviral effects of human placenta hydrolysate (Laennec

Eun-Ha Kim, Young-Il Kim, Seung-Gyu Jang, Minju Im, Kyeongsoo Jeong, Young Ki Choi, Hae-Jung Han

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of microbiology (Seoul, Korea), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  3. Article
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  5. Article
  6. Ferrets: A powerful model of SARS-CoV-2.Zoological research · 2023
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Eun-Ha KimCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, 28644, Republic of Korea.
Young-Il KimCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, 28644, Republic of Korea.
Seung-Gyu JangCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, 28644, Republic of Korea.
Minju ImGREENCROSS WellBeing Co., Ltd., Seoul, 07335, Republic of Korea.
Kyeongsoo JeongGREENCROSS WellBeing Co., Ltd., Seoul, 07335, Republic of Korea.
Young Ki ChoiCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, 28644, Republic of Korea. choiki55@chungbuk.ac.kr.
Hae-Jung HanGREENCROSS WellBeing Co., Ltd., Seoul, 07335, Republic of Korea. hjhan@gccorp.com.
Chungbuk National University · KRGreen Cross (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has caused unprecedented health, social, and economic crises worldwide. However, to date, there is an only a limited effective treatment for this disease. Human placenta hydrolysate (hPH) has previously been shown to be safe and to improve the health condition in patients with hyperferritinemia and COVID-19. In this study, we aimed to determine the antiviral effects of hPH against SARS-CoV-2 in vitro and in vivo models and compared with Remdesivir, an FDA-approved drug for COVID-19 treatment. To assess whether hPH inhibited SARS-CoV-2 replication, we determined the CC

Indexed as

COVID-19 Drug TreatmentProtein HydrolysatesAdenosine MonophosphateAlanineAnimalsAntiviral AgentsChlorocebus aethiopsFemaleFerretsHumansMalePlacentaPregnancySARS-CoV-2Vero CellsVirus ReplicationAdenosine MonophosphateAlanineAntiviral AgentsProtein HydrolysatesremdesivirantiviralferretinterferonLaennec®SARS-CoV-2

Identifiers

PMID34613605
PMCPMC8493534
OpenAlexW3204633271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.