ReviewSports medicine (Auckland, N.Z.)2022
Is there Evidence for the Suggestion that Fatigue Accumulates Following Resistance Exercise?
Review in Sports medicine (Auckland, N.Z.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Influence of Resistance Training Proximity-to-Failure on Skeletal Muscle Hypertrophy: A Systematic Review with Meta-analysis.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Trial
- Trial
- Post-exercise home-based hot-bathing with/without light exercise: effects on physiological adaptations to short-term high-intensity resistance training in healthy young men.European journal of applied physiology · 2026Article
- Effects of a 5-Day Back Squat Overreaching Protocol on Strength Performance, Perceived Recovery and Wellness Responses: A Pilot Trial.Journal of functional morphology and kinesiology · 2025Article
- Assessment of muscle fatigability using isometric repetitive handgrip strength in frail older adults. A cross-sectional study.Journal of translational medicine · 2025Article
- Effect of home-based hot bathing on exercise-induced adaptations associated with short-term resistance exercise training in young men.Physiological reports · 2025Article
- Relationship between 10 repetition maximum for chest press, leg press, and muscle mass measured using bioelectrical impedance analysis in healthy young adults.Journal of physical therapy science · 2025Article
- Statistical flaws of the fitness-fatigue sports performance prediction model.Scientific reports · 2025Article
- Quantification of weekly strength-training volume per muscle group in competitive physique athletes.Frontiers in sports and active living · 2025Article
- The effect of transcranial pulse current stimulation on the accumulation of exercise-induced fatigue in college students after moderate intensity exercise evidence from central and peripheral sources.Frontiers in physiology · 2025Article
- The Effects of Acute Deep Seawater Supplementation on Muscle Function after Triathlon.Journal of clinical medicine · 2024Article
- Deloading Practices in Strength and Physique Sports: A Cross-sectional Survey.Sports medicine - open · 2024Article
- Mild to moderate damage in knee extensor muscles accumulates after two bouts of maximal eccentric contractions.European journal of applied physiology · 2023Article
- Muscular Adaptations Between Very Low Load Resistance Training With Pulsed Direct Current Stimulation (Neubie) and Traditional High Load Training.Journal of musculoskeletal & neuronal interactions · 2023Article
- The acute muscular response following a novel form of pulsed direct current stimulation (Neubie) or traditional resistance exercise.Journal of musculoskeletal & neuronal interactions · 2022Article
- Exe-Muscle: An Exercised Human Skeletal Muscle Gene Expression Database.International journal of environmental research and public health · 2022Article
- "I Want to Create So Much Stimulus That Adaptation Goes Through the Roof": High-Performance Strength Coaches' Perceptions of Planned Overreaching.Frontiers in sports and active living · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been suggested that improper post-exercise recovery or improper sequence of training may result in an 'accumulation' of fatigue. Despite this suggestion, there is a lack of clarity regarding which physiological mechanisms may be proposed to contribute to fatigue accumulation. The present paper explores the time course of the changes in various fatigue-related measures in order to understand how they may accumulate or lessen over time following an exercise bout or in the context of an exercise program. Regarding peripheral fatigue, the depletion of energy substrates and accumulation of metabolic byproducts has been demonstrated to occur following an acute bout of resistance training; however, peripheral accumulation and depletion appear unlikely candidates to accumulate over time. A number of mechanisms may contribute to the development of central fatigue, postulating the need for prolonged periods of recovery; however, a time course is difficult to determine and is dependent on which measurement is examined. In addition, it has not been demonstrated that central fatigue measures accumulate over time. A potential candidate that may be interpreted as accumulated fatigue is muscle damage, which shares similar characteristics (i.e., prolonged strength loss). Due to the delayed appearance of muscle damage, it may be interpreted as accumulated fatigue. Overall, evidence for the presence of fatigue accumulation with resistance training is equivocal, making it difficult to draw the conclusion that fatigue accumulates. Considerable work remains as to whether fatigue can accumulate over time. Future studies are warranted to elucidate potential mechanisms underlying the concept of fatigue accumulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.