Evidence map›Paper›PMID 34613588›Full record

ArticleNeurotoxicity research2021

Lacidipine Attenuates Symptoms of Nicotine Withdrawal in Mice.

Kunal Khurana, Manish Kumar, Nitin Bansal

Abstract read
PubMed Publisher
In one paragraph

Article in Neurotoxicity research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Therapeutic Potential of Methanolic Extract ofJournal of pharmacopuncture · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Kunal KhuranaI. K. Gujral Punjab Technical University, Kapurthala (Punjab) 144603, India.ORCID http://orcid.org/0000-0002-7593-5439
Manish KumarChitkara College of Pharmacy, Chitkara University, Punjab, India.ORCID http://orcid.org/0000-0001-6697-544X
Nitin BansalDepartment of Pharmacology, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy, Bela (Ropar) 140111, India. pharmacy@cblu.ac.in.ORCID http://orcid.org/0000-0002-2792-7469
Chaudhary Devi Lal University · INChitkara University · INPunjab Technical University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotine-withdrawal after daily exposure manifests somatic and affective symptom including a range of cognitive deficits. Earlier studies suggested participation of L-type calcium channels (LTCCs) in development of nicotine dependence and expression of withdrawal signs. An upsurge in Ca

Indexed as

3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl esterAnimalsBrainCalcium Channel BlockersCalcium Channels, L-TypeCatalaseDihydropyridinesElevated Plus Maze TestFemaleGlutathioneHindlimb SuspensionLipid PeroxidationMaleMiceNicotineSubstance Withdrawal Syndrome3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl esterCalcium Channel BlockersCalcium Channels, L-TypeCatalaseDihydropyridinesGlutathionelacidipineNicotineSuperoxide DismutaseAnxietyBay-K8644DepressionLacidipineMemoryNicotine

Identifiers

PMID34613588
OpenAlexW3177108346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.