ArticleResearch on child and adolescent psychopathology2022
Blunted Flanker P300 Demonstrates Specificity to Depressive Symptoms in Females during Adolescence.
Article in Research on child and adolescent psychopathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 23 citations in OpenAlex.
- Blunted No-Go P3 predicts faster increases in disordered eating symptoms in early adolescents: A four-wave longitudinal study.Research square · 2026Article
- Childhood P300 predicts development of depressive disorders into adolescence.Cognitive, affective & behavioral neuroscience · 2026Article
- Association Between Early Childhood P300 Deficits and Risk for Preadolescence Depressive Disorder Mediated by Responsiveness to PCIT-ED Treatment.Research on child and adolescent psychopathology · 2025Article
- The Go/No-Go P3 and Depressive Symptoms in Adolescents: Trial-Level Change and Mean Amplitude Relate Differently to Anhedonic Versus Negative Mood Symptoms.Research on child and adolescent psychopathology · 2025Article
- Attenuated Doors-Locked P300 Amplitude and Elevated Depressive Symptoms: Effects of Age and Sex in Two Independent Samples of Youth.Psychophysiology · 2025Article
- The P3 ERP in Relation to General Versus Specific Psychopathology in Early Childhood.Research on child and adolescent psychopathology · 2023Article
- Deficits in doors P300 amplitude during adolescence associated with preschool-onset depression.Psychophysiology · 2023Article
- Reliability and stability of oddball P300 amplitude in older adults: The role of stimulus sequence effects.Brain and cognition · 2023Article
- Reduced P300 amplitude is consistently associated with trait anhedonia across repeated assessments.Psychophysiology · 2022Article
- The P300, loneliness, and depression in older adults.Biological psychology · 2022Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
Recent research suggests that depressive disorders in adults are characterized by reductions in flanker P300 amplitude, and that a reduced flanker P300 may also predict worst depressive trajectories over time. The current study extended this work to adolescence-and to evaluate the specificity of the relationship between flanker P300 to depressive symptoms versus anxiety symptoms, and whether the association between flanker P300 and depressive symptoms was moderated by biological sex. To this end, P300 amplitude, depression, anxiety, and sex were assessed in a large sample of 619 adolescents aged 11 to 14. Participants completed a speeded response flanker task while EEG was recorded, as well as self-reported measures of current depression and anxiety symptoms. Reduced P300 amplitude was related to both heightened depression and anxiety symptoms in zero-order correlations. Regression-based analyses suggest that reduced P300 was uniquely related to depressive symptoms. Furthermore, this negative association between P300 and depression was apparent in female adolescents, but not male adolescents. In sum, the current study suggests that flanker P300 amplitude may potentially serve as a neural marker specific to depression in females during adolescence.
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