Evidence map›Paper›PMID 34613221›Full record

ArticleApplied optics2021

Broadband absorption spectroscopy of heterogeneous biological tissue.

Giles Blaney, Phillip Curtsmith, Angelo Sassaroli, Cristianne Fernandez, Sergio Fantini

Open access · greenAbstract read
In one paragraph

Article in Applied optics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Giles Blaney
Phillip Curtsmith
Angelo Sassaroli
Cristianne Fernandez
Sergio Fantini
Tufts University · US

Funding

Coherent hemodynamics spectroscopy for cerebral autoregulation and blood flowR01NS095334 · NINDS · TUFTS UNIVERSITY MEDFORD · PI FANTINI, SERGIO · 2016 to 2020
$2.6M
NINDS NIH HHS R01 NS095334
6 · The paper itself

Abstract

Absorption spectra (∼600 to 1064 nm) of six tissues in three healthy volunteers were measured by combining dual-slope continuous-wave broadband spectroscopy with self-calibrated frequency-domain measurements of scattering at two wavelengths (690 and 830 nm). The spectral fit with a linear combination of oxy- and deoxyhemoglobin, water, and lipids extinction spectra is improved by a wavelength-independent absorption background. The need to introduce this background is assigned to the inhomogeneous distribution of absorbers in tissue. By using a two-layer model, the relationship between recovered concentrations and their two-layer values was investigated, and the implications for non-invasive tissue spectroscopy are discussed.

Indexed as

Adipose TissueAdultBody WaterBreastFemaleHealthy VolunteersHemoglobinsHumansLipidsMaleMuscle, SkeletalOxyhemoglobinsSpectroscopy, Near-InfraredYoung AdultdeoxyhemoglobinHemoglobinsLipidsOxyhemoglobins

Identifiers

PMID34613221
PMCPMC11407782
OpenAlexW3181283591

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.