Evidence map›Paper›PMID 34612792›Full record

ArticleJournal of clinical and experimental neuropsychology2021

Cognition during active methamphetamine use versus remission.

Marilyn Huckans, Stephen Boyd, Grant Moncrief, Nathan Hantke, Bethany Winters, Kate Shirley, Emily Sano, Holly McCready, Laura Dennis, Milky Kohno and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical and experimental neuropsychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Methamphetamine dependence in Australia-why is 'ice' (crystal meth) so addictive?Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Marilyn HuckansResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
Stephen BoydDepartment of Anesthesia and Perioperative Medicine, Oregon Health & Science University, Portland, Or, USA.
Grant MoncriefResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
Nathan HantkeResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
Bethany WintersResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
Kate ShirleyResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
Emily SanoResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
Holly McCreadyResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
Laura DennisResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
Milky KohnoResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
William HoffmanResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
Jennifer M LoftisResearch & Development Service, Veterans Affairs Portland Health Care System, Portland, OR, USA.
VA Portland Health Care System · USOregon Health & Science University · USPacific University Oregon · US

Funding

Traditional Service Core [Translational Service Core (TSC)]P50DA018165 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI PHILLIPS, TAMARA J. · 2006 to 2016
$13.0M
BIOLOGICAL BASES OF ALCOHOLISMT32AA007468 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Andrey E Ryabinin · 1987 to 2026
$11.3M
BIOLOGICAL BASES OF DRUG-SEEKING BEHAVIORT32DA007262 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILLIAMS, JOHN T · 1991 to 2022
$9.4M
Validation of CD74 as a treatment target for methamphetamine use disorderU18DA052351 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI HUCKANS, MARILYN, LOFTIS, JENNIFER M · 2020 to 2020
$199k
BLRD VA I01 BX000517BLRD VA I01 BX002061CSRD VA I01 CX001558CSRD VA IK2 CX001790NIAAA NIH HHS T32 AA007468NIDA NIH HHS P50 DA018165NIDA NIH HHS T32 DA007262NIDA NIH HHS U18 DA052351
6 · The paper itself

Abstract

objectiveTo evaluate whether cognitive performance in adults with active methamphetamine use (MA-ACT) differs from cognitive performance in adults in remission from MA use disorder (MA-REM) and adults without a history of substance use disorder (CTLs).

methodMA-ACT (n = 36), MA-REM (n = 48), and CTLs (n = 62) completed the Neuropsychological Assessment Battery (NAB).

resultsThe MA-ACT group did not perform significantly worse than CTLs on any NAB Index. The MA-REM group performed significantly (p < 0.050) worse than CTLs on the NAB Memory Index. The MA-ACT group performed significantly better than CTLs and the MA-REM group on the Executive Functions Index.

conclusionsSome cognitive deficits are apparent during remission from MA use, but not during active use; this may result in clinical challenges for adults attempting to maintain recovery and continue with treatment.

Indexed as

Amphetamine-Related DisordersMethamphetamineAdultCognitionExecutive FunctionHumansNeuropsychological TestsMethamphetamineaddictionCognitiondependenceneuropsychologicalstimulantsubstance use disorder

Identifiers

PMID34612792
PMCPMC8979254
OpenAlexW3204098789

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.