Evidence map›Paper›PMID 34612057›Full record

Observational studyJournal of the American Heart Association2021

Prognostic Importance of Pulmonary Arterial Capacitance in Acute Decompensated Heart Failure With Preserved Ejection Fraction.

Akito Nakagawa, Yoshio Yasumura, Chikako Yoshida, Takahiro Okumura, Jun Tateishi, Junichi Yoshida, Haruhiko Abe, Shunsuke Tamaki, Masamichi Yano, Takaharu Hayashi and 7 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 1 country.

Akito NakagawaDivision of Cardiovascular Medicine Amagasaki-Chuo Hospital Amagasaki Japan.ORCID 0000-0001-8276-1505
Yoshio YasumuraDivision of Cardiovascular Medicine Amagasaki-Chuo Hospital Amagasaki Japan.
Chikako YoshidaDivision of Cardiovascular Medicine Amagasaki-Chuo Hospital Amagasaki Japan.
Takahiro OkumuraDivision of Cardiovascular Medicine Amagasaki-Chuo Hospital Amagasaki Japan.
Jun TateishiDivision of Cardiovascular Medicine Amagasaki-Chuo Hospital Amagasaki Japan.
Junichi YoshidaDivision of Cardiovascular Medicine Amagasaki-Chuo Hospital Amagasaki Japan.
Haruhiko AbeCardiovascular Division National Hospital Organization Osaka National Hospital Osaka Japan.
Shunsuke TamakiDivision of Cardiology Osaka General Medical Center Osaka Japan.
Masamichi YanoDivision of Cardiology Osaka Rosai Hospital Sakai Japan.
Takaharu HayashiDivision of Cardiology Osaka Police Hospital Osaka Japan.ORCID 0000-0003-1637-4536
Yusuke NakagawaDivision of Cardiology Kawanishi City Hospital Hyogo Japan.
Takahisa YamadaDivision of Cardiology Osaka General Medical Center Osaka Japan.
Tomoharu DohiDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Suita Japan.
Daisaku NakataniDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Suita Japan.
Shungo HikosoDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Suita Japan.ORCID 0000-0003-2284-1970
Yasushi SakataDepartment of Cardiovascular Medicine Osaka University Graduate School of Medicine Suita Japan.ORCID 0000-0002-5618-4721
Osaka CardioVascular Conference (OCVC)‐Heart Failure investigators
The University of Osaka · JPOsaka Prefectural Medical Center · JPOsaka National Hospital · JPOsaka Police Hospital · JPOsaka Rosai Hospital · JPToyo Institute of Food Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Although the prognostic importance of pulmonary arterial capacitance (PAC; stroke volume/pulmonary arterial pulse pressure) has been elucidated in heart failure with reduced ejection fraction, whether its significance in patients suffering from heart failure with preserved ejection fraction is not known. We aimed to examine the association of PAC with outcomes in inpatients with heart failure with preserved ejection fraction. Methods and Results We prospectively studied 705 patients (median age, 83 years; 55% women) registered in PURSUIT-HFpEF (Prospective Multicenter Observational Study of Patients With Heart Failure With Preserved Ejection Fraction). We investigated the association of echocardiographic PAC at discharge with the primary end point of all-cause death or heart failure rehospitalization with a mean follow-up of 384 days. We further tested the acceptability of the prognostic significance of PAC in a subgroup of patients (167/705 patients; median age, 81 years; 53% women) in whom PAC was assessed by right heart catheterization. The median echocardiographic PAC was 2.52 mL/mm Hg, with a quartile range of 1.78 to 3.32 mL/mm Hg. Univariable and multivariable Cox regression testing revealed that echocardiographic PAC was associated with the primary end point (unadjusted hazard ratio, 0.82; 95% CI, 0.72-0.92;

Indexed as

Heart FailureHypertension, PulmonaryPulmonary ArteryVascular CapacitanceAged, 80 and overFemaleHumansMalePrognosisProspective StudiesStroke VolumeVentricular Function, LefthemodynamicsHFpEFprognosispulmonary arterial capacitancepulmonary circulationright ventricular–pulmonary arterial coupling

Identifiers

PMID34612057
PMCPMC8751883
OpenAlexW3204676059

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.