Evidence map›Paper›PMID 34611761›Full record

SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021

Postnatal diagnosis of single-suture craniosynostosis with cranial ultrasound: a systematic review.

Ian Whittall, William A Lambert, Douglas J Moote, Markus J Bookland, Jonathan E Martin, Christopher D Hughes, David S Hersh

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ian WhittallUConn School of Medicine, Farmington, CT, USA.
William A LambertUConn School of Medicine, Farmington, CT, USA.
Douglas J MooteDivision of Radiology, Connecticut Children's, Hartford, CT, USA.
Markus J BooklandDivision of Neurosurgery, Connecticut Children's, Hartford, CT, USA.
Jonathan E MartinDivision of Neurosurgery, Connecticut Children's, Hartford, CT, USA.
Christopher D HughesDepartment of Surgery, UConn School of Medicine, Farmington, CT, USA.
David S HershDivision of Neurosurgery, Connecticut Children's, Hartford, CT, USA. dhersh@connecticutchildrens.org.ORCID 0000-0003-1177-2201
Connecticut Children's Medical Center · USUConn Health · US

Funding

Thrasher Research Fund Early Career Award
6 · The paper itself

Abstract

introductionThe optimal protocol for diagnostic workup of craniosynostosis and the role of specific imaging modalities remain controversial. Skull X-rays and 3-dimensional head CTs are options when physical exam is equivocal but involve ionizing radiation. Ultrasound has emerged as an alternative modality for visualization of cranial sutures, but its use is not widespread.

methodsThe authors performed a systematic review of the literature on the use of ultrasound for the diagnosis of craniosynostosis.

resultsA total of 12 studies involving 1062 patients were included. Overall, 300 patients (28.2%) were diagnosed with craniosynostosis. A total of 369 (34.7%) patients had their diagnosis (craniosynostosis vs. patent sutures) confirmed with another imaging modality in addition to ultrasound. Among studies, the specificity of ultrasound ranged from 86 to 100%, and the sensitivity from 71 to 100%.

conclusionsUltrasonography of cranial sutures is a feasible and accurate tool for the diagnosis of single-suture craniosynostosis when physical exam findings are insufficient. Although technical aspects of ultrasonography and its interpretation have an associated learning curve, ultrasound can achieve high sensitivity and specificity among patients with suspected craniosynostosis.

Indexed as

CraniosynostosesCranial SuturesHumansInfantRadiographySuturesUltrasonographyCraniosynostosisPostnatalSutureUltrasound

Identifiers

PMID34611761
OpenAlexW3204576653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.