Evidence map›Paper›PMID 34611649›Full record

ArticleAmerican journal of preventive cardiology2021

Characteristics of Transgender Women Referred to Women's Heart Clinic.

Madeline K Mahowald, Arvind K Maheshwari, Kyla M Lara-Breitinger, Fadi W Adel, Patricia A Pellikka, Caroline J Davidge-Pitts, Todd B Nippoldt, Birgit Kantor, Rekha Mankad

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Article in American journal of preventive cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. LGBTQ+ cardiovascular health equity: a brief review.Frontiers in cardiovascular medicine · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Madeline K MahowaldDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Arvind K MaheshwariDivision of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, Mayo Clinic, Rochester, MN.
Kyla M Lara-BreitingerDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Fadi W AdelDepartment of Internal Medicine, Mayo Clinic, Rochester, MN.
Patricia A PellikkaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Caroline J Davidge-PittsDivision of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, Mayo Clinic, Rochester, MN.
Todd B NippoldtDivision of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, Mayo Clinic, Rochester, MN.
Birgit KantorDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Rekha MankadDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTransgender women have been reported to have a high burden of cardiovascular disease (CVD) and risk factors based largely on surveys. Our aim was to describe the prevalence of CVD and associated comorbidities among a cohort of older transgender women referred to cardiology as part of their gender-affirming care.

methodsThis was a retrospective, cross-sectional study of transgender women at a single institution from 2017 to 2019.

resultsFifty-two consecutive patients were included. The most common reasons for referral were cardiac risk factor management (45%) and pre-operative cardiac risk stratification prior to gender-affirming surgery (35%). The mean age was 57 ± 10 years, 87% were white, and 92% had insurance coverage. Forty-eight patients (92%) were taking gender-affirming hormone therapy; 5 had undergone breast augmentation, 4 had undergone orchiectomy, and 2 had undergone vaginoplasty. The most common comorbidities were depression and/or anxiety (63%), obesity (58%), and hyperlipidemia (54%). Excluding aldosterone antagonists, 46% were on cardiac medications; changes were recommended for 25% of patients: new prescriptions in 9, dose adjustments in 5, and discontinuations in 4. According to the pooled cohort equation, the 10-year risk of atherosclerotic CVD was 9.4 ± 7.7% when the study population was calculated as male and 5.2 ± 5.1% when calculated as female (

conclusionsOlder transgender women may have an underestimated prevalence of CVD and its risk factors. More research is needed to identify cardiovascular health profiles, improve practice consistency, and establish normative values for transgender patients.

Indexed as

Clinical cardiologyEndocrinologyHealthcare accessWomen and minorities

Identifiers

PMID34611649
PMCPMC8387274

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.