Evidence map›Paper›PMID 34611639›Full record

ArticleAmerican journal of preventive cardiology2021

The beneficial effect over 3 years by pictorial information to patients and their physician about subclinical atherosclerosis and cardiovascular risk: Results from the VIPVIZA randomized clinical trial.

Anna Bengtsson, Margareta Norberg, Nawi Ng, Bo Carlberg, Christer Grönlund, Johan Hultdin, Bernt Lindahl, Bertil Lindahl, Steven Nordin, Emma Nyman and 3 more

Abstract read
In one paragraph

Article in American journal of preventive cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  11. Evaluation of Cardiovascular Risk in People with Type 1 Diabetes: A Comprehensive and Specific Proposed Practical Approach.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anna BengtssonDepartment of Public Health and Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden.
Margareta NorbergDepartment of Epidemiology and Global Health, Umeå University, Umeå, Sweden.
Nawi NgDepartment of Epidemiology and Global Health, Umeå University, Umeå, Sweden.
Bo CarlbergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden.
Christer GrönlundDepartment of Radiation Sciences, Umeå University, Umeå, Sweden.
Johan HultdinDepartment of Medical Biosciences, Clinical Chemistry, Umeå University, Umeå, Sweden.
Bernt LindahlDepartment of Public Health and Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden.
Bertil LindahlDepartment of Medical Sciences and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Steven NordinDepartment of Psychology, Umeå University, Umeå, Sweden.
Emma NymanDepartment of Public Health and Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden.
Patrik WennbergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden.
Per WesterDepartment of Public Health and Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden.
Ulf NäslundDepartment of Public Health and Clinical Medicine, Umeå University, Umeå SE-901 87, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNon-adherence to guidelines and preventive measures is a major challenge, particularly so to obtain long-term adherence to lifestyle changes and recommended medication. The objective was to investigate if pictorial information regarding subclinical carotid atherosclerosis provided to individuals and physicians gave sustained effects on cardiovascular risk beyond the previously reported effect after 1 year and up to 3 years.

methodsA Prospective Randomized Open Blinded End-point (PROBE) trial. Within a CVD prevention program in Västerbotten County, Sweden, 3532 healthy individuals aged 40, 50 or 60 years were enrolled and 1:1 randomized to intervention (

resultsA beneficial effect on cardiovascular risk was observed at 3-year follow-up; Framingham Risk Score (FRS) was 13.38 for the intervention group and 14.08 for the control group (

conclusionsThis study provides evidence of sustained beneficial effects on the adherence to prevention guidelines over 3 years of pictorial information about subclinical carotid atherosclerosis, resulting in lower cardiovascular risk regardless of sex and educational level. Direct visualization of the underlying still subclinical atherosclerotic disease, rather than just indirect information about risk factors and statistical risk of future myocardial infarction, stroke and death, is one way to tackle the problem of non-adherence to prevention of cardiovascular diseases.

Indexed as

AtherosclerosisCardiovascular diseaseCarotid ultrasoundPrevention

Identifiers

PMID34611639
PMCPMC8387279

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.