Evidence map›Paper›PMID 34611612›Full record

ArticleiScience2021

Sleeping ribosomes: Bacterial signaling triggers RaiA mediated persistence to aminoglycosides.

Manon Lang, Evelyne Krin, Chloé Korlowski, Odile Sismeiro, Hugo Varet, Jean-Yves Coppée, Didier Mazel, Zeynep Baharoglu

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 47 citations in OpenAlex.

  1. Ribosome hibernation in zinc-starvedMicrobiology spectrum · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Detection and Characterization of the Eukaryotic Vacant Ribosome.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Indole-3-acetic acid (IAA) protectsApplied and environmental microbiology · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Genetic disruption of the bacterialProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Hibernating ribosomes as drug targets?Frontiers in microbiology · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Manon LangDépartement Génomes et Génétique, Institut Pasteur, UMR3525, CNRS, Unité Plasticité du Génome Bactérien, 75015 Paris, France.
Evelyne KrinDépartement Génomes et Génétique, Institut Pasteur, UMR3525, CNRS, Unité Plasticité du Génome Bactérien, 75015 Paris, France.
Chloé KorlowskiDépartement Génomes et Génétique, Institut Pasteur, UMR3525, CNRS, Unité Plasticité du Génome Bactérien, 75015 Paris, France.
Odile SismeiroBiomics Technological Platform, Center for Technological Resources and Research, Institut Pasteur, 75015 Paris, France.
Hugo VaretBiomics Technological Platform, Center for Technological Resources and Research, Institut Pasteur, 75015 Paris, France.
Jean-Yves CoppéeBiomics Technological Platform, Center for Technological Resources and Research, Institut Pasteur, 75015 Paris, France.
Didier MazelDépartement Génomes et Génétique, Institut Pasteur, UMR3525, CNRS, Unité Plasticité du Génome Bactérien, 75015 Paris, France.
Zeynep BaharogluDépartement Génomes et Génétique, Institut Pasteur, UMR3525, CNRS, Unité Plasticité du Génome Bactérien, 75015 Paris, France.
Centre National de la Recherche Scientifique · FRInstitut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indole is a molecule proposed to be involved in bacterial signaling. We find that indole secretion is induced by sublethal tobramycin concentrations and increases persistence to aminoglycosides in

Indexed as

BacteriologyMicrobial genomicsViral microbiology

Identifiers

PMID34611612
PMCPMC8476650
OpenAlexW3201404109

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.