Evidence map›Paper›PMID 34611451›Full record

ArticleRisk management and healthcare policy2021

AB Blood Group Confers Higher Risk for Primary Brain Tumors in Pediatrics.

Abdulrahman Al Shudifat, Hala Al Suqi, Kutada Soub, Leen Al Nemrawi, Moa'tasem Abu Jaber, Mohammad Al Barbarawi, Nour Shewaikani, Yazan El Adwan, Assem Al Refaei

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Article in Risk management and healthcare policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Abdulrahman Al ShudifatDepartment of Neurosurgery, University of Jordan, Amman, Jordan.
Hala Al SuqiSchool of Medicine, University of Jordan, Amman, Jordan.
Kutada SoubDepartment of Neurosurgery, University of Jordan, Amman, Jordan.
Leen Al NemrawiSchool of Medicine, University of Jordan, Amman, Jordan.
Moa'tasem Abu JaberSchool of Medicine, University of Jordan, Amman, Jordan.
Mohammad Al BarbarawiDepartment of Neurosurgery, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Nour ShewaikaniSchool of Medicine, University of Jordan, Amman, Jordan.
Yazan El AdwanJordan Hospital, Amman, Jordan.
Assem Al RefaeiSchool of Medicine, University of Jordan, Amman, Jordan.ORCID 0000-0002-4592-4448
University of Jordan · JOJordan Hospital · JOJordan University of Science and Technology · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur current study investigates the relationship between ABO blood groups and brain tumor incidence in the Jordanian pediatric population in a case-controlled manner. PATIENTS AND

methodsThis case-control study targeted pediatric primary brain tumor patients and tumor-free controls. Cases included patients younger than 18 when given a histologically confirmed diagnosis with a primary brain tumor, ascertained from two tertiary hospitals in Jordan. Controls were age- and gender-matched to cases and acquired from JUH pediatric clinics, with an exclusion for all patients with a personal history of tumors. Through using available records and calling guardians, our team obtained patients' and controls' blood groups.

resultsOur case control included 81 (35.4%) pediatric primary brain tumor patients and age- and gender-matched tumor-free controls 148 (64.6%). When compared to O blood group, patients with A and B blood groups were not at higher risk of developing pediatric primary brain tumors (P=0.742, P=1.000, respectively). However, Chi-square analysis revealed a 2.79-fold higher risk for pediatric primary brain tumors in AB blood group patients (P=0.024). Gender-specific analysis revealed a 3.42-fold higher risk for pediatric brain tumors in AB blood group males when compared to O blood group males.

conclusionThis work represents the first published study on the association between blood groups and pediatric brain tumors. With future research with larger samples and control of confounding factors, AB blood group may become a more established risk factor for pediatric brain tumors, aiding in screening.

Indexed as

ABO blood groupsbrain tumorschildrenpediatrics

Identifiers

PMID34611451
PMCPMC8486269
OpenAlexW3203697600

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.