Evidence map›Paper›PMID 34611432›Full record

ArticleInternational journal of general medicine2021

Evaluation of Ferroptosis-related Gene

Zeyu Zhang, Xiangyuan Qiu, Yuanliang Yan, Qiujiu Liang, Yuan Cai, Bi Peng, Zhijie Xu, Fada Xia

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  16. ConcomitantJournal of breast cancer · 2023
    Article
  17. Journal of gastrointestinal oncology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zeyu ZhangDepartment of Thyroid Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Xiangyuan QiuDepartment of Thyroid Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Yuanliang YanDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Qiujiu LiangDepartment of Pharmacy, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Yuan CaiDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Bi PengDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Zhijie XuDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, People's Republic of China.ORCID 0000-0003-2047-883X
Fada XiaDepartment of Thyroid Surgery, Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFerroptosis is the latest-discovered, iron-dependent form of regulated cell death. It has been increasingly recognized that ferroptosis-related genes participate in oncogenesis and development of cancers, including breast cancer (

methodsTranscriptome microarray datasets (GSE22358, GSE9014 and GSE8977, GSE2990 and GSE2034) and TCGA-

resultsTwo ferroptosis-related genes (

conclusionThis study firstly demonstrated that ferroptosis-related gene,

Indexed as

AKR1C1breast cancerferroptosisimmune infiltrationimmune microenvironment

Identifiers

PMID34611432
PMCPMC8487294
OpenAlexW3202889953

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.