Evidence map›Paper›PMID 34611400›Full record

ReviewInternational journal of nanomedicine2021

Current Trends and Challenges in Pharmacoeconomic Aspects of Nanocarriers as Drug Delivery Systems for Cancer Treatment.

Sylwia Milewska, Katarzyna Niemirowicz-Laskowska, Gabriela Siemiaszko, Piotr Nowicki, Agnieszka Z Wilczewska, Halina Car

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
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  5. Review
  6. Polymeric Nanocarriers with pH-Dependent Release for Tumor-Specific Delivery.Recent advances in drug delivery and formulation · 2026
    Review
  7. Review
  8. Review
  9. Article
  10. Anti-QS Strategies AgainstMicroorganisms · 2025
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sylwia MilewskaDepartment of Experimental Pharmacology, Medical University of Bialystok, Bialystok, 15-361, Poland.ORCID 0000-0002-6362-8132
Katarzyna Niemirowicz-LaskowskaDepartment of Experimental Pharmacology, Medical University of Bialystok, Bialystok, 15-361, Poland.ORCID 0000-0002-3311-7147
Gabriela SiemiaszkoFaculty of Chemistry, University of Bialystok, Bialystok, 15-245, Poland.
Piotr NowickiDepartment of Experimental Pharmacology, Medical University of Bialystok, Bialystok, 15-361, Poland.
Agnieszka Z WilczewskaFaculty of Chemistry, University of Bialystok, Bialystok, 15-245, Poland.
Halina CarDepartment of Experimental Pharmacology, Medical University of Bialystok, Bialystok, 15-361, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotherapy is a part of nanomedicine that involves nanoparticles as carriers to deliver drugs to target locations. This novel targeting approach has been found to resolve various problems, especially those associated with cancer treatment. In nanotherapy, the carrier plays a crucial role in handling many of the existing challenges, including drug protection before early-stage degradations of active substances, allowing them to reach targeted cells and overcome cell resistance mechanisms. The present review comprises the following sections: the first part presents the introduction of pharmacoeconomics as a branch of healthcare economics, the second part covers various beneficial aspects of the use of nanocarriers for in vitro, in vivo, and pre- and clinical studies, as well as discussion on drug resistance problem and present solutions to overcome it. In the third part, progress in drug manufacturing and optimization of the process of nanoparticle synthesis were discussed. Finally, pharmacokinetic and toxicological properties of nanoformulations due to up-to-date studies were summarized. In this review, the most recent developments in the field of nanotechnology's economic impact, particularly beneficial applications in medicine were presented. Primarily focus on cancer treatment, but also discussion on other fields of application, which are strongly associated with cancer epidemiology and treatment, was made. In addition, the current limitations of nanomedicine and its huge potential to improve and develop the health care system were presented.

Indexed as

NanoparticlesNeoplasmsDrug CarriersDrug Delivery SystemsEconomics, PharmaceuticalNanomedicineDrug Carriersclinical trialsnanomaterials synthesisnanotechnologypharmacoeconomic analysispharmacoeconomicspharmacology

Identifiers

PMID34611400
PMCPMC8487283

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.