ArticleScientific reports2021
Ppia is the most stable housekeeping gene for qRT-PCR normalization in kidneys of three Pkd1-deficient mouse models.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 24 citations in OpenAlex.
- Association between dim light melatonin onset predicted from gene expression profiles with sleep time and chronotype preference: A pilot study.Chronobiology international · 2025Trial
- Integrin α 1 β 1 Promotes Interstitial Fibrosis and Cyst Growth in a Mouse Model of Polycystic Kidney Disease.Journal of the American Society of Nephrology : JASN · 2026Article
- Translational regulation of PKD1 by evolutionarily conserved upstream open reading frames.RNA biology · 2025Review
- Selecting Optimal Housekeeping Genes for RT-qPCR in Endometrial Cancer Studies: A Narrative Review.International journal of molecular sciences · 2025Review
- Article
- Cartilaginous fishes-derived chondroitin sulfates potentially suppress lipid droplet accumulation in the differentiated 3T3-L1 adipocytes.Glycoconjugate journal · 2025Article
- Selection and validation of reference genes for quantitative real-time PCR during the developmental stages of seeds inFrontiers in plant science · 2025Article
- Article
- Activation of limbal epithelial proliferation is partly controlled by the ACE2-LCN2 pathway.iScience · 2024Article
- Housekeeping gene expression variability in differentiating and non-differentiating 3T3-L1 cells.Adipocyte · 2023Article
- Optimal reference genes for RNA tissue analysis in small animal models of hemorrhagic fever viruses.Scientific reports · 2023Article
- TMPRSS2 Impacts Cytokine Expression in Murine Dendritic Cells.Biomedicines · 2023Article
- Lymphocyte deficiency alters the transcriptomes of oligodendrocytes, but not astrocytes or microglia.PloS one · 2023Article
- Determination of reference genes as a quantitative standard for gene expression analysis in mouse mesangial cells stimulated with TGF-β.Scientific reports · 2022Article
- Characterization of Adrenal miRNA-Based Dysregulations in Cushing's Syndrome.International journal of molecular sciences · 2022Article
- Prenatal exposure to the phthalate DEHP impacts reproduction-related gene expression in the pituitary.Reproductive toxicology (Elmsford, N.Y.) · 2022Article
- Investigation of chicken housekeeping genes using next-generation sequencing data.Frontiers in genetics · 2022Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common inherited renal disorder, characterized by renal cyst development leading to end-stage renal disease. Although the appropriate choice of suitable reference is critical for quantitative RNA analysis, no comparison of frequently used "housekeeping" genes is available. Here, we determined the validity of 7 candidate housekeeping genes (Actb, Actg1, B2m, Gapdh, Hprt, Pgam1 and Ppia) in kidney tissues from mouse models orthologous to ADPKD, including a cystic mice (CY) 10-12 weeks old (Pkd1
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