Evidence map›Paper›PMID 34611232›Full record

ArticleScientific reports2021

Major bacterial isolate and antibiotic resistance from routine clinical samples in Southern Ethiopia.

Mengistu Hailemariam, Tsegaye Alemayehu, Bereket Tadesse, Netsanete Nigussie, Asnakech Agegnehu, Techilo Habtemariam, Mulubrhan Ali, Enkosilassie Mitiku, Elshaday Azerefegne

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

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  15. Antimicrobial Resistance Profile ofEthiopian journal of health sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mengistu HailemariamSchool of Medical Laboratory Science, Hawassa University College of Medicine and Health Sciences, P.O. Box 1560, Hawassa, Ethiopia. mengemariamzenebe@gmail.com.
Tsegaye AlemayehuSchool of Medical Laboratory Science, Hawassa University College of Medicine and Health Sciences, P.O. Box 1560, Hawassa, Ethiopia.
Bereket TadesseHawassa University Comprehensive and Specialized Hospital, Hawassa, Ethiopia.
Netsanete NigussieHawassa University Comprehensive and Specialized Hospital, Hawassa, Ethiopia.
Asnakech AgegnehuHawassa University Comprehensive and Specialized Hospital, Hawassa, Ethiopia.
Techilo HabtemariamHawassa University Comprehensive and Specialized Hospital, Hawassa, Ethiopia.
Mulubrhan AliSchool of Medical Laboratory Science, Hawassa University College of Medicine and Health Sciences, P.O. Box 1560, Hawassa, Ethiopia.
Enkosilassie MitikuHawassa University Comprehensive and Specialized Hospital, Hawassa, Ethiopia.
Elshaday AzerefegneHawassa University Comprehensive and Specialized Hospital, Hawassa, Ethiopia.
Hawassa University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, antibiotic-resistant bacterial infections are a challenge for the health care system. Although physicians demand timely drug resistance data to guide empirical treatment, local data is rather scarce. Hence, this study performed a retrospective analysis of microbiological findings at the Hawassa public hospital. Secondary data were retrieved to assess the prevalence and level of drug resistance for the most common bacterial isolates from clinical samples processed at Hawassa University Comprehensive Specialized Hospital. Out of 1085 clinical samples processed in the microbiology laboratory, the prevalence of bacterial infection was 32.6%. Bacterial bloodstream infection was higher in children than in adults (OR, 4; 95% CI 1.8-14.6; p = 0.005). E. coli and K. pneumoniae were the commonest bacterial isolate both in children (36.8%, 26.3%) and in adults (33.3%, 26.7%) from the urine sample while, the leading bacteria identified from the CSF sample was P. aeruginosa, 37% in children and 43% in adult. In this study, all identified bacterial isolates were multi-drug resistant (MDR) ranging from 50 to 91%. The highest proportion of MDR was S. aureus 91.1 followed by K. pneumoniae 87.6%. Since the nationwide investigation of bacterial isolate, and drug resistance is rare in Ethiopia, a report from such type of local surveillance is highly useful to guide empirical therapy by providing awareness on the level resistance of isolates.

Indexed as

Drug Resistance, BacterialAdolescentAdultAnti-Bacterial AgentsBacteriaBacterial InfectionsChildChild, PreschoolCross InfectionCross-Sectional StudiesDrug Resistance, Multiple, BacterialEthiopiaFemaleHumansInfantInfant, NewbornAnti-Bacterial Agents

Identifiers

PMID34611232
PMCPMC8492677
OpenAlexW3202758454

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.