ArticleScientific reports2021
The relationship between ultrasound findings and thyroid function in children and adolescent autoimmune diffuse thyroid diseases.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 10 citations in OpenAlex.
- Obesity-related thyroid reflections: from weight gain to weight loss.European thyroid journal · 2026Review
- Nomogram for predicting difficult transoral and submental thyroidectomy: a retrospective model development and validation study with large-scale population.Surgical endoscopy · 2025Article
- Principles and features of ultrasound hypoechogenicity in diffuse thyroid pathology.Quantitative imaging in medicine and surgery · 2024Review
- Subacute thyroiditis paranchime heterogeneity may mask thyroid nodules and higher EU-TIRADS scores.Endocrine · 2022Observational
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To evaluate the association between thyroid echogenicity and heterogeneity seen on ultrasonography (US) and thyroid function in pediatric and adolescent populations with autoimmune diffuse thyroid diseases (AITD). From 2000 to 2020, we reviewed thyroid ultrasound (US) images and thyroid function statuses in 133 children and adolescent AITD patients. Our review of the images focused on decreased echogenicity and heterogeneity, which were classified into four grades. Among patients with overt hypothyroidism or overt hyperthyroidism, 94.2% (65/69) showed a US grade of 3 or 4. In patients with subclinical hyper/hypothyroidism or euthyroidism, 45.3% (29/64) showed grades 1 or 2. There were no overt hyper/hypothyroidism patients with US grade 1. When we compared US grades according to thyroid status, more severe thyroid dysfunction was significantly associated with higher US grade (p = 0.047). Thyroid stimulating hormone (TSH) level differed significantly according to US grades when we evaluated hyperthyroid (p = 0.035) and hypothyroid (p = 0.027) states independently. 11 patients showed both US grade and thyroid function status changes on follow-up US. In children and adolescent AITD patients, there was an association between decreased echogenicity and heterogeneity on US and thyroid dysfunction.
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