Evidence map›Paper›PMID 34611205›Full record

ArticleScientific reports2021

Perioperative Doppler measurements of renal perfusion are associated with acute kidney injury in patients undergoing cardiac surgery.

Johan Lyngklip Hermansen, Gabriela Pettey, Heidi Tofte Sørensen, Samantha Nel, Nqoba Tsabedze, Arne Hørlyck, Palesa Motshabi Chakane, Henrik Gammelager, Peter Juhl-Olsen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Johan Lyngklip HermansenDepartment of Cardiothoracic and Vascular Surgery, Anaesthesia Section, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark. johanfhermansen@gmail.com.
Gabriela PetteyDepartment of Anaesthesiology, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, 17 Jubilee Road, Parktown, Johannesburg, 2193, South Africa.
Heidi Tofte SørensenDepartment of Cardiothoracic and Vascular Surgery, Anaesthesia Section, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Samantha NelDivision of Cardiology, Department of Internal Medicine, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, 17 Jubilee Road, Parktown, Johannesburg, 2193, South Africa.
Nqoba TsabedzeDivision of Cardiology, Department of Internal Medicine, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, 17 Jubilee Road, Parktown, Johannesburg, 2193, South Africa.
Arne HørlyckDepartment of Radiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Palesa Motshabi ChakaneDepartment of Anaesthesiology, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, 17 Jubilee Road, Parktown, Johannesburg, 2193, South Africa.
Henrik GammelagerDepartment of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 82, 8200, Aarhus N, Denmark.
Peter Juhl-OlsenDepartment of Cardiothoracic and Vascular Surgery, Anaesthesia Section, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Aarhus University Hospital · DKUniversity of the Witwatersrand · ZAJohannesburg Hospital · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is a frequent and severe complication in cardiac surgery. Normal renal function is dependent on adequate renal perfusion, which may be altered in the perioperative period. Renal perfusion can be assessed with Doppler measurement. We aimed to determine the association between Doppler measurements of renal perfusion and the development of AKI. This was a prospective, observational study of 100 patients with ≥ one risk factor for postoperative AKI undergoing open-heart surgery. Doppler ultrasound examinations were performed before surgery and on the first and fourth postoperative day. AKI was defined according to the KDIGO criteria and subdivided into mild (KDIGO stage 1) and severe AKI (KDIGO stage 2 + 3). Thirty-three patients developed AKI, 25 developed mild and eight developed severe AKI. Abnormal renal venous flow pattern on the first postoperative day was significantly associated with the development of severe AKI (OR 8.54 (95% CI 1.01; 72.2), P = 0.046), as were portal pulsatility fraction (OR 1.07 (95% CI 1.02; 1.13), P = 0.005). Point-of-care Doppler ultrasound measurements of renal perfusion are associated with the development of AKI after cardiac surgery. Renal and portal Doppler ultrasonography can be used to identify patients at high risk or very low risk of AKI after cardiac surgery.

Indexed as

Perioperative CareUltrasonography, DopplerAcute Kidney InjuryCardiac Surgical ProceduresComorbidityHumansKidneyPortal VeinProspective StudiesRenal Circulation

Identifiers

PMID34611205
PMCPMC8492663
OpenAlexW3201902426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.