Evidence map›Paper›PMID 34611199›Full record

ArticleScientific reports2021

Asymptomatic individuals can increase the final epidemic size under adaptive human behavior.

Baltazar Espinoza, Madhav Marathe, Samarth Swarup, Mugdha Thakur

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  7. Social dilemma of nonpharmaceutical interventions: Determinants of dynamic compliance and behavioral shifts.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Baltazar EspinozaBiocomplexity Institute and Initiative, Network Systems Science and Advanced Computing Division, University of Virginia, Charlottesville, VA, USA. baltazar.espinoza@virginia.edu.
Madhav MaratheBiocomplexity Institute and Initiative, Network Systems Science and Advanced Computing Division, University of Virginia, Charlottesville, VA, USA.
Samarth SwarupBiocomplexity Institute and Initiative, Network Systems Science and Advanced Computing Division, University of Virginia, Charlottesville, VA, USA.
Mugdha ThakurBiocomplexity Institute and Initiative, Network Systems Science and Advanced Computing Division, University of Virginia, Charlottesville, VA, USA.
Biocom · US

Funding

Systems Analysis of Social Pathways of Epidemics to Reduce Health DisparitiesR01GM109718 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MARATHE, ACHLA, VULLIKANTI, ANIL · 2014 to 2022
$3.6M
CDC HHS 75D30119C05935NIGMS NIH HHS R01 GM109718NIH HHS 1R01 GM109718NIH HHS 1R01GM109718
6 · The paper itself

Abstract

Infections produced by non-symptomatic (pre-symptomatic and asymptomatic) individuals have been identified as major drivers of COVID-19 transmission. Non-symptomatic individuals, unaware of the infection risk they pose to others, may perceive themselves-and be perceived by others-as not presenting a risk of infection. Yet, many epidemiological models currently in use do not include a behavioral component, and do not address the potential consequences of risk misperception. To study the impact of behavioral adaptations to the perceived infection risk, we use a mathematical model that incorporates the behavioral decisions of individuals, based on a projection of the system's future state over a finite planning horizon. We found that individuals' risk misperception in the presence of non-symptomatic individuals may increase or reduce the final epidemic size. Moreover, under behavioral response the impact of non-symptomatic infections is modulated by symptomatic individuals' behavior. Finally, we found that there is an optimal planning horizon that minimizes the final epidemic size.

Indexed as

BehaviorAsymptomatic DiseasesCOVID-19HumansModels, TheoreticalPerceptionSARS-CoV-2

Identifiers

PMID34611199
PMCPMC8492713
OpenAlexW3202047392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.