ArticleNPJ Parkinson's disease2021
Arm swing responsiveness to dopaminergic medication in Parkinson's disease depends on task complexity.
Article in NPJ Parkinson's disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Backward Walking as a Rehabilitation Strategy in Parkinson's Disease: A Focused Systematic Review.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Association between Backward Walking and Cognition in Parkinson Disease: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Objective Measurement of Walking Activity Using Wearable Technologies in People with Parkinson Disease: A Systematic Review.Sensors (Basel, Switzerland) · 2022Pooled it
- Instrumented Timed Up and Go Analysis Identifies Biomechanical Markers Across Early Hoehn and Yahr Stages of Parkinson's Disease.Sensors (Basel, Switzerland) · 2026Article
- Whole body analysis of functional communities and topological features of gait with different speeds in Parkinson's disease.Journal of neurology · 2026Article
- Effects of Levodopa on Gait in People With Parkinson's Disease With and Without a History of Falls.Movement disorders clinical practice · 2025Article
- Abnormal arm swing movements in Parkinson's disease: onset, progression and response to L-Dopa.Journal of neuroengineering and rehabilitation · 2025Article
- Quantifying arm swing in Parkinson's disease: a method accounting for arm activities during free-living gait.Journal of neuroengineering and rehabilitation · 2025Article
- Modeling and validation of wearable sensor-based gait parameters in Parkinson's disease patients with cognitive impairment.Frontiers in aging neuroscience · 2025Article
- Rhythmic auditory cues improve gait asymmetry during unobstructed walking in people with Parkinson's disease but have no effect on obstacle avoidance - AsymmGait-Parkinson study.Frontiers in aging neuroscience · 2025Article
- Predicting executive functioning from walking features in Parkinson's disease using machine learning.Scientific reports · 2024Article
- Inter-joint coordination with and without dopaminergic medication in Parkinson's disease: a case-control study.Journal of neuroengineering and rehabilitation · 2024Article
- Machine Learning Models for Parkinson Disease: Systematic Review.JMIR medical informatics · 2024Review
- The effect of dopaminergic treatment on whole body kinematics explored through network theory.Scientific reports · 2024Article
- Identifying Subtle Motor Deficits Before Parkinson's Disease is Diagnosed: What to Look for?Journal of Parkinson's disease · 2024Review
- Nordic walking and arm swing asymmetry in people with Parkinson's disease: protocol for a randomised clinical trial.BMJ open sport & exercise medicine · 2024Article
- Rate control deficits during pinch grip and ankle dorsiflexion in early-stage Parkinson's disease.PloS one · 2023Article
- Step-Counting Accuracy of a Commercial Smartwatch in Mild-to-Moderate PD Patients and Effect of Spatiotemporal Gait Parameters, Laterality of Symptoms, Pharmacological State, and Clinical Variables.Sensors (Basel, Switzerland) · 2022Article
- Article
- Evaluation of Arm Swing Features and Asymmetry during Gait in Parkinson's Disease Using the Azure Kinect Sensor.Sensors (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
The evidence of the responsiveness of dopaminergic medication on gait in patients with Parkinson's disease is contradicting. This could be due to differences in complexity of the context gait was in performed. This study analysed the effect of dopaminergic medication on arm swing, an important movement during walking, in different contexts. Forty-five patients with Parkinson's disease were measured when walking at preferred speed, fast speed, and dual-tasking conditions in both OFF and ON medication states. At preferred, and even more at fast speed, arm swing improved with medication. However, during dual-tasking, there were only small or even negative effects of medication on arm swing. Assuming that dual-task walking most closely reflects real-life situations, the results suggest that the effect of dopaminergic medication on mobility-relevant movements, such as arm swing, might be small in everyday conditions. This should motivate further studies to look at medication effects on mobility in Parkinson's disease, as it could have highly relevant implications for Parkinson's disease treatment and counselling.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.