Evidence map›Paper›PMID 34611028›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Altered Response Dynamics and Increased Population Correlation to Tonal Stimuli Embedded in Noise in Aging Auditory Cortex.

Kelson Shilling-Scrivo, Jonah Mittelstadt, Patrick O Kanold

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Aging in the Primary Auditory Cortex.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Dark exposure reduces high-frequency hearing loss in C57BL/6J mice.bioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Adaptation in auditory processing.Physiological reviews · 2023
    Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Kelson Shilling-ScrivoDepartment of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland 21230.
Jonah MittelstadtDepartment of Biology, University of Maryland, College Park, Maryland 20742.ORCID 0000-0001-6738-5556
Patrick O KanoldDepartment of Biology, University of Maryland, College Park, Maryland 20742 pkanold@jhu.edu.ORCID 0000-0002-7529-5435
Johns Hopkins University · USUniversity of Maryland, Baltimore · USUniversity of Maryland, College Park · US

Funding

Speech Perception with High Cognitive DemandP01AG055365 · NIA · UNIV OF MARYLAND, COLLEGE PARK · PI GORDON-SALANT, SANDRA M · 2017 to 2021
$8.4M
NEURONAL CIRCUITS AND PLASTICITY OF NEONATAL AUDITORY CORTEXR01DC009607 · NIDCD · UNIV OF MARYLAND, COLLEGE PARK · PI PATRICK O KANOLD · 2009 to 2026
$7.8M
COMPARATIVE AND EVOLUTIONARY BIOLOGY OF HEARINGT32DC000046 · NIDCD · UNIV OF MARYLAND, COLLEGE PARK · PI Catherine Emily Carr, Matthew J. Goupell · 1994 to 2026
$7.5M
NIA NIH HHS P01 AG055365NIDCD NIH HHS R01 DC009607NIDCD NIH HHS T32 DC000046
6 · The paper itself

Abstract

Age-related hearing loss (presbycusis) is a chronic health condition that affects one-third of the world population. One hallmark of presbycusis is a difficulty hearing in noisy environments. Presbycusis can be separated into two components: alterations of peripheral mechanotransduction of sound in the cochlea and central alterations of auditory processing areas of the brain. Although the effects of the aging cochlea in hearing loss have been well studied, the role of the aging brain in hearing loss is less well understood. Therefore, to examine how age-related central processing changes affect hearing in noisy environments, we used a mouse model (Thy1-GCaMP6s X CBA) that has excellent peripheral hearing in old age. We used

Indexed as

AgingAnimalsAuditory CortexFemaleMaleMiceMice, Inbred CBANeuronsPresbycusisagingauditory cortexcorrelationnoiseoffsetpopulation

Identifiers

PMID34611028
PMCPMC8612470
OpenAlexW3202656338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.