Evidence map›Paper›PMID 34610849›Full record

ArticleChinese neurosurgical journal2021

Treatment delay from aneurysmal subarachnoid hemorrhage to endovascular treatment: a high-volume hospital experience.

Xiaoxi Zhang, Haishuang Tang, Qiao Zuo, Gaici Xue, Guoli Duan, Yi Xu, Bo Hong, Rui Zhao, Pengfei Yang, Jianmin Liu and 1 more

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In one paragraph

Article in Chinese neurosurgical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaoxi Zhang *Department of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China.
Haishuang Tang *Department of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China.
Qiao Zuo *Department of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China.
Gaici XueDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China.
Guoli DuanDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China.
Yi XuDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China.
Bo HongDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China.
Rui ZhaoDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China.
Pengfei YangDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China.
Jianmin LiuDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China.
Qinghai HuangDepartment of Neurosurgery, Changhai Hospital, Naval Military Medical University, 168 Changhai Rd, Shanghai, 200433, People's Republic of China. 1016996030@qq.com.

Funding

Key Technology Research and Development Program of Shandong (CN) 2016YFC1300700National Natural Science Foundation of China 81701136National Natural Science Foundation of China 81771264
6 · The paper itself

Abstract

backgroundEarly treatment for patients with aneurysmal subarachnoid hemorrhage (aSAH) could significantly reduce the risk of re-bleeding and improve clinical outcomes. We assessed the different time intervals from the initial hemorrhage, admission, and endovascular treatment and identified the risk factors contributing to delay.

methodsBetween February 2017 and December 2019, 422 consecutive aSAH patients treated in a high-volume hospital were collected and reviewed. Risk factors contributing to admission delay and treatment delay were analyzed with univariate and multivariate analysis.

resultsOne hundred twenty-two (28.9%) were admitted to the high-volume hospital at the day of symptom onset and 386 (91.5%) were treated with endovascular management at the same day of admission. The multivariate analysis found that younger age (P = 0.022, OR = 0.981, 95% CI 0.964-0.997) and good Fisher score (P = 0.002, OR = 0.420, 95% CI 0.245-0.721) were independent risk factors of admission delay. None was found to be related with treatment delay. Multivariate analysis (OR (95% CI)) showed that higher age 1.027 (1.004-1.050), poorer Fisher score 3.496 (1.993-6.135), larger aneurysmal size 1.112 (1.017-1.216), and shorter interval between onset to admission 1.845 (1.018-3.344) were independent risk factors of poorer clinical outcome.

conclusionTreatment delay was mainly caused by pre-hospital delay including delayed admission and delayed transfer. Our experience showed that cerebrovascular team could provide early treatment for aSAH patients. Younger age and good Fisher score were significantly related with admission delay. However, admission delay was further significantly correlated with better clinical outcome.

Indexed as

Coiling with stent placementIntracranial aneurysm, RuptureProcedure-related complicationSafety

Identifiers

PMID34610849
PMCPMC8493710

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