ArticleCirculation research2021
Matricellular Protein Cilp1 Promotes Myocardial Fibrosis in Response to Myocardial Infarction.
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Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
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Who cites it
35 citing papers in PubMed, 49 citations in OpenAlex.
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- Involvement of Fibulin-5 in endothelial to mesenchymal transition leading to cardiac fibrosis during metabolic syndrome.Journal of translational medicine · 2026Article
- Pacemaker implantation is associated with post-ablation atrial fibrillation recurrence mediated by plasma CILP1.Scientific reports · 2026Article
- Clinical prognostic value of cartilage intermediate layer protein 1 (CILP-1) in elderly patients with acute myocardial infarction.BMC cardiovascular disorders · 2026Article
- BMP1 inhibitor UK383367 improves MI-induced cardiac remodeling and fibrosis in mice via ameliorating macrophage polarization and mitochondrial dysfunction.Acta pharmacologica Sinica · 2026Article
- Effective Components and Molecular Mechanism of Biejiaruangan Capsule Against Liver Fibrosis: High-resolution Mass Spectrometry, Network Pharmacological Analysis and Experimental Verification.Combinatorial chemistry & high throughput screening · 2026Article
- Direct aldosterone stimulation of skeletal muscle fibroblasts changes gene expression and differentially affects fibroblast functions from normal and diseased muscles.Frontiers in physiology · 2026Article
- CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.Cell death & disease · 2025Article
- SALL4 mediates SHP2 inhibition in myocardial fibroblasts through the DOT1L/H3K79me2 signaling pathway to promote the progression of myocardial infarction.Scientific reports · 2024Article
- Fibroblast-specific TGF-β signaling mediates cardiac dysfunction, fibrosis, and hypertrophy in obese diabetic mice.Cardiovascular research · 2024Article
- Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways.Journal of cardiovascular translational research · 2024Article
- The prognostic value of cartilage intermediate layer protein 1 (CILP1) in patients with diabetic cardiomyopathy.BMC cardiovascular disorders · 2024Article
- Integrative proteomic and metabolomic elucidation of cardiomyopathy with in vivo and in vitro models and clinical samples.Molecular therapy : the journal of the American Society of Gene Therapy · 2024Review
- Microparticle Mediated Delivery of Apelin Improves Heart Function in Post Myocardial Infarction Mice.Circulation research · 2024Article
- Repair of the Infarcted Heart: Cellular Effectors, Molecular Mechanisms and Therapeutic Opportunities.Circulation research · 2024Review
- Single-cell analysis reveals a subpopulation of adipose progenitor cells that impairs glucose homeostasis.Nature communications · 2024Article
- Exploring the molecular biology of ischemic cardiomyopathy based on ferroptosis‑related genes.Experimental and therapeutic medicine · 2024Article
- Analysis of immunoinfiltration and EndoMT based on TGF-β signaling pathway-related genes in acute myocardial infarction.Scientific reports · 2024Article
- Article
- NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
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Authors and funding
18 authors at 7 institutions in 4 countries.
Qing-Jun Zhang *Internal Medicine-Cardiology Division (Q.-J.Z., M.Z., X.L., J.A.H., D.C., R.L.L., R.Z., Z.-P.L.), UT Southwestern Medical Center, Dallas, TX.
Yu He *Department of Clinical Laboratory, First Affiliated hospital of Guangxi Medical University, China (Y.H.).
Yongnan Li *The Sixth General Surgery, Biliary & Vascular surgery, Shengjing Hospital of China Medical University, China (Y.L.).ORCID 0000-0001-8622-4424
Huali ShenInstitutes of Biochemical Science, Fudan University, China (H.S., L.L.).ORCID 0000-0002-0255-3720
Ling LinInstitutes of Biochemical Science, Fudan University, China (H.S., L.L.).ORCID 0000-0002-6766-5432
Min ZhuInternal Medicine-Cardiology Division (Q.-J.Z., M.Z., X.L., J.A.H., D.C., R.L.L., R.Z., Z.-P.L.), UT Southwestern Medical Center, Dallas, TX.
Zhaoning WangDepartment of Molecular Biology (Z.W., J.A.H., J.M., Z.-P.L.), UT Southwestern Medical Center, Dallas, TX.ORCID 0000-0002-0290-4746
Xiang LuoInternal Medicine-Cardiology Division (Q.-J.Z., M.Z., X.L., J.A.H., D.C., R.L.L., R.Z., Z.-P.L.), UT Southwestern Medical Center, Dallas, TX.ORCID 0000-0002-7647-6094
Joseph A HillInternal Medicine-Cardiology Division (Q.-J.Z., M.Z., X.L., J.A.H., D.C., R.L.L., R.Z., Z.-P.L.), UT Southwestern Medical Center, Dallas, TX.
Dian CaoInternal Medicine-Cardiology Division (Q.-J.Z., M.Z., X.L., J.A.H., D.C., R.L.L., R.Z., Z.-P.L.), UT Southwestern Medical Center, Dallas, TX.
Richard L LuoInternal Medicine-Cardiology Division (Q.-J.Z., M.Z., X.L., J.A.H., D.C., R.L.L., R.Z., Z.-P.L.), UT Southwestern Medical Center, Dallas, TX.
Raymond ZouInternal Medicine-Cardiology Division (Q.-J.Z., M.Z., X.L., J.A.H., D.C., R.L.L., R.Z., Z.-P.L.), UT Southwestern Medical Center, Dallas, TX.
John McAnallyDepartment of Molecular Biology (Z.W., J.A.H., J.M., Z.-P.L.), UT Southwestern Medical Center, Dallas, TX.ORCID 0000-0001-6938-2703
Jun LiaoDepartment of Bioengineering, University of Texas at Arlington (J.L.).
Pietro BajonaDepartment of Cardiovascular and Thoracic Surgery (P.B.), UT Southwestern Medical Center, Dallas, TX.
Qun S ZangDepartment of Surgery, Stritch School of Medicine, Burn & Shock Trauma Research Institute, Loyola University, Maywood, IL (Q.S.Z.).ORCID 0000-0002-6397-8896
Yonghao YuDepartment of Biochemistry (Y.Y.), UT Southwestern Medical Center, Dallas, TX.
Zhi-Ping LiuInternal Medicine-Cardiology Division (Q.-J.Z., M.Z., X.L., J.A.H., D.C., R.L.L., R.Z., Z.-P.L.), UT Southwestern Medical Center, Dallas, TX.ORCID 0000-0003-1341-3878
Southwestern Medical Center · USFudan University · CNAllegheny Health Network · USChina Medical University · CNFirst Affiliated Hospital of GuangXi Medical University · CNLoyola University Chicago · USThe University of Texas at Arlington · US
Funding
PATHOPHYSIOLOGY OF MYOCARDIAL DISEASEST32HL007227 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Chulan Kwon, WENDY S POST · 1985 to 2026
$21.2MPathological Responses to Mitochondrial ROS in Sepsis-Induced Cardiac DysfunctionR01GM111295 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI ZANG, QUN SOPHIA · 2014 to 2022
$2.7MCardiomyocyte bromodomain protein 4 (BRD4) in physiology and diseaseR01HL147933 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HILL, JOSEPH A · 2020 to 2023
$2.5MRole of Cilp1 in Post-Natal Heart Response to InjuryR01HL157050 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI LIU, ZHI-PING · 2022 to 2025
$2.2MTargeting KDM4B, a novel alternative splicing regulator, in castration-resistant prostate cancer (CRPC)R01CA215063 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI HSIEH, JER-TSONG, LIU, ZHI-PING · 2018 to 2022
$1.9MMechanisms of obesity-dependent alterations in cardiomyocyte metabolismR01HL128215 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HILL, JOSEPH A · 2017 to 2020
$1.6MFoxO-dependent Control of Cardiovascular RemodelingR01HL126012 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HILL, JOSEPH A · 2016 to 2019
$1.6MEpigenetic Regulation of Cardiac Hypertrophy and Heart FailureR01HL109471 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI LIU, ZHI-PING · 2012 to 2015
$1.6MLaser Scanning Confocal for UT Southwestern Live Cell Imaging FacilityS10OD021684 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI LUBY-PHELPS, KATHERINE J · 2016 to 2016
$455kNCI NIH HHS R01 CA215063NHLBI NIH HHS R01 HL109471NHLBI NIH HHS R01 HL126012NHLBI NIH HHS R01 HL128215NHLBI NIH HHS R01 HL147933NHLBI NIH HHS R01 HL157050NHLBI NIH HHS T32 HL007227NIGMS NIH HHS R01 GM111295NIH HHS S10 OD021684
Abstract
[Figure: see text].
Indexed as
AnimalsCells, CulturedFibrosisHEK293 CellsHumansMechanistic Target of Rapamycin Complex 1MiceMice, Inbred C57BLMyocardial InfarctionMyocardiumMyofibroblastsPyrophosphatasesCILP protein, mouseMechanistic Target of Rapamycin Complex 1Pyrophosphatasesbiomarkerscollagenextracellular matrixfibrosismyocardial infarctionmyofibroblasts
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.