Evidence map›Paper›PMID 34610302›Full record

ArticleCell reports2021

Divergent outputs of the ventral lateral geniculate nucleus mediate visually evoked defensive behaviors.

Lindsey D Salay, Andrew D Huberman

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
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  3. Tail-rattling in rodents: more than a threat display.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Review
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  13. Ambient Light Impacts Innate Behaviors of New-World and Old-World Mice.bioRxiv : the preprint server for biology · 2025
    Article
  14. Behavioral Modulation and Molecular Definition of Wide-Field Vertical Cells in the Mouse Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lindsey D SalayDepartment of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Andrew D HubermanDepartment of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA 94305, USA; BioX, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: adh1@stanford.edu.
Stanford University · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

Rapid alternations between exploration and defensive reactions require ongoing risk assessment. How visual cues and internal states flexibly modulate the selection of behaviors remains incompletely understood. Here, we show that the ventral lateral geniculate nucleus (vLGN)-a major retinorecipient structure-is a critical node in the network controlling defensive behaviors to visual threats. We find that vLGN

Indexed as

Behavior, AnimalLightAnimalsCalciumGABAergic NeuronsHeart RateMaleMiceMice, Inbred C57BLMice, TransgenicMidline Thalamic NucleiSuperior ColliculiVentral Thalamic NucleiVisual PathwaysCalciumanxietyfearretinathalamusvisualvLGN

Identifiers

PMID34610302
PMCPMC10954303
OpenAlexW3203982671

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.