Evidence map›Paper›PMID 34610254›Full record

Trial reportJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics2021

The Effects of Topical Timolol and Latanoprost on Calculated Ocular Perfusion Pressure in Nonglaucomatous Volunteers.

Ajay Kolli, Carol B Toris, David M Reed, Jesse Gilbert, Arthur J Sit, Vikas Gulati, Arash Kazemi, Shan Fan, David C Musch, Sayoko E Moroi

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ajay KolliDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-3026-8636
Carol B TorisDepartment of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID 0000-0003-3794-6142
David M ReedDepartment of Ophthalmology and Visual Sciences, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.ORCID 0000-0002-4772-6138
Jesse GilbertDepartment of Ophthalmology and Visual Sciences, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Arthur J SitDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.
Vikas GulatiDepartment of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Arash KazemiDepartment of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.
Shan FanDepartment of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, Nebraska, USA.
David C MuschDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.
Sayoko E MoroiDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-0418-0657
The Ohio State University Wexner Medical Center · USUniversity of Michigan · USMayo Clinic · USUniversity of Nebraska Medical Center · US

Funding

Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Genomic Resource Grant for the PhenX Toolkit - expansion and sustainabilityPhenX Supplement for COVID-19 ResearchU41HG007050 · NHGRI · RESEARCH TRIANGLE INSTITUTE · PI HAMILTON, CAROL MARIE · 2013 to 2022
$21.2M
VIVARIUM MODULEP30EY007003 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David Antonetti · 1987 to 2026
$17.6M
Aqueous Humor Dynamic Components that Determine Intraocular Pressure VarianceR01EY022124 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOROI, SAYOKO E · 2012 to 2022
$3.6M
NCATS NIH HHS UL1 TR000433NEI NIH HHS P30 EY007003NEI NIH HHS R01 EY022124NHGRI NIH HHS U41 HG007050
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood PressureCross-Over StudiesFemaleHealthy VolunteersHumansIntraocular PressureLatanoprostMaleMiddle AgedOcular Physiological PhenomenaOphthalmic SolutionsProspective StudiesTimololLatanoprostOphthalmic SolutionsTimolollatanoprostocular perfusion pressuretimolol

Identifiers

PMID34610254
PMCPMC8713568
OpenAlexW3204243408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.