Evidence map›Paper›PMID 34610012›Full record

ArticlePloS one2021

Prevalence of bacteriologically confirmed pulmonary tuberculosis and associated risk factors: A community survey in Thirvallur District, south India.

Chandra Kumar Dolla, Bhaskaran Dhanaraj, Padmapriyadarsini Chandrasekaran, Sriram Selvaraj, Pradeep Aravindan Menon, Kannan Thiruvengadam, Rajendran Krishnan, Rajesh Mondal, Muniyandi Malaisamy, Srinivasa B Marinaik and 2 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  11. Article
  12. Risk Factors for Tuberculosis in Elderly: Prevalence and Population-attributable Risk.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Chandra Kumar DollaDepartment of Epidemiology, ICMR-National Institute for Research in Tuberculosis, Chennai, India.ORCID 0000-0003-2978-3267
Bhaskaran DhanarajDepartment of Clinical Research, ICMR-National Institute for Research in Tuberculosis, Chennai, India.
Padmapriyadarsini ChandrasekaranDepartment of Clinical Research, ICMR-National Institute for Research in Tuberculosis, Chennai, India.
Sriram SelvarajDepartment of Epidemiology, ICMR-National Institute for Research in Tuberculosis, Chennai, India.ORCID 0000-0003-0369-6640
Pradeep Aravindan MenonDepartment of Epidemiology, ICMR-National Institute for Research in Tuberculosis, Chennai, India.
Kannan ThiruvengadamDepartment of Statistics, Epidemiology Unit, ICMR-National Institute for Research in Tuberculosis, Chennai, India.
Rajendran KrishnanDepartment of Statistics, Epidemiology Unit, ICMR-National Institute for Research in Tuberculosis, Chennai, India.
Rajesh MondalDepartment of Bacteriology, ICMR-National Institute for Research in Tuberculosis, Chennai, India.
Muniyandi MalaisamyDepartment of Health Economics, ICMR-National Institute for Research in Tuberculosis, Chennai, India.
Srinivasa B MarinaikDepartment of Epidemiology, ICMR-National Institute for Research in Tuberculosis, Chennai, India.
Lakshmi MuraliDistrict Tuberculosis Centre, MoHFW, Government of Tamil Nadu, Thiruvallur, Chennai, India.
Srikanth Prasad TripathyICMR-National Institute for Research in Tuberculosis, Chennai, India.
National Institute of Research in Tuberculosis · INGovernment of Tamil Nadu · IN

Funding

World Health Organization
6 · The paper itself

Abstract

backgroundTuberculosis (TB) prevalence surveys add to the active case detection in the community level burden of TB both national and regional levels. The aim of this study was to assess the prevalence of bacteriologically confirmed pulmonary tuberculosis (PTB) in the community.

methodsHousehold community-based tuberculosis disease survey was conducted targeting 69054 population from 43 villages of 5 blocks in Tiruvallure district adopting cluster sampling methodology of ≥15 years old adult rural population of South India during 2015-2018. All eligible individuals with suspected symptoms of PTB were screened with chest X-ray. Two sputum specimens (one spot and the other early morning sample) were collected for M.tb smear and culture examination. Conversely demographical, smoking and alcohol drinking habits information were also collected to explore the risk factor. Stepwise logistic regression was employed to associate risk factors for PTB.

resultsA total of 62494 were screened among 69054 eligible population, of whom 6340 were eligible for sputum specimen collection. Sputum for M.tb smear and culture examination were collected in 93% of participants. The derived prevalence of PTB was 307/100000 population (smear-positive 130; culture positive 277). As expected that PTB has decreased substantially compared to preceding surveys and it showed that older age, male, low BMI, diabetes, earlier history of TB and alcohol users were significantly associated (p < .0001) with an increased risk of developing PTB.

conclusionUpshot of the active survey has established a reduction in the prevalence of PTB in the rural area which can be accredited to better programmatic implementation and success of the National TB Control Programme in this district. It also has highlighted the need for risk reduction interventions accelerate faster elimination of TB.

Indexed as

AdolescentAdultCross-Sectional StudiesFemaleHumansIndiaLogistic ModelsMaleMiddle AgedMycobacterium tuberculosisPrevalenceRisk FactorsRural PopulationSputumSurveys and QuestionnairesTuberculosis, Pulmonary

Identifiers

PMID34610012
PMCPMC8491886
OpenAlexW3204039348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.