Evidence map›Paper›PMID 34609900›Full record

ArticleThe British journal of radiology2022

MRI-directed biopsy for primary detection of prostate cancer in a population of 223 men: MRI In-Bore vs MRI-transrectal ultrasound fusion-targeted techniques.

Maurizio Del Monte, Stefano Cipollari, Francesco Del Giudice, Martina Pecoraro, Marco Bicchetti, Emanuele Messina, Ailin Dehghanpour, Antonio Ciardi, Alessandro Sciarra, Carlo Catalano and 1 more

Abstract readComparative Study
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  11. The combined value of mpUS and mpMRI-TRUS fusion for the diagnosis of clinically significant prostate cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
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  12. Article
  13. Innovations in prostate cancer: introductory editorial.The British journal of radiology · 2022
    Article
  14. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maurizio Del MonteDepartment of Radiological Sciences, Oncology and Pathology, Sapienza/Policlinico Umberto I, Rome, Italy.
Stefano CipollariDepartment of Radiological Sciences, Oncology and Pathology, Sapienza/Policlinico Umberto I, Rome, Italy.ORCID 0000-0002-7430-8628
Francesco Del GiudiceDepartment of Maternal-Infant and Urological Sciences, Sapienza/Policlinico Umberto I, Rome, Italy.
Martina PecoraroDepartment of Radiological Sciences, Oncology and Pathology, Sapienza/Policlinico Umberto I, Rome, Italy.
Marco BicchettiDepartment of Radiological Sciences, Oncology and Pathology, Sapienza/Policlinico Umberto I, Rome, Italy.
Emanuele MessinaDepartment of Radiological Sciences, Oncology and Pathology, Sapienza/Policlinico Umberto I, Rome, Italy.
Ailin DehghanpourDepartment of Radiological Sciences, Oncology and Pathology, Sapienza/Policlinico Umberto I, Rome, Italy.
Antonio CiardiDepartment of Radiological Sciences, Oncology and Pathology, Sapienza/Policlinico Umberto I, Rome, Italy.
Alessandro SciarraDepartment of Maternal-Infant and Urological Sciences, Sapienza/Policlinico Umberto I, Rome, Italy.
Carlo CatalanoDepartment of Radiological Sciences, Oncology and Pathology, Sapienza/Policlinico Umberto I, Rome, Italy.
Valeria PanebiancoDepartment of Radiological Sciences, Oncology and Pathology, Sapienza/Policlinico Umberto I, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the detection rates of overall prostate cancer (PCa) and clinically significant PCa (csPCa) and the median percentage of cancer per biopsy core between MRI-guided In-bore and MRI-TRUS fusion-targeted biopsy (TBx).

methodsIn this retrospective study, 223 patients who underwent prostate multiparametric MRI (mpMRI) and subsequent MR-directed biopsy were included. For PCa and csPCa detection rate (DR), contingency tables were tested via the Pearson's chi-squared to explore the variance of the outcome distribution. The percentage of cancer per biopsy core was tested with a two-tailed Mann-Withney test.

resultsOne hundred and seventeen and 106 patients underwent MRI-TRUS fusion or MRI In-bore TBx, respectively. 402 MRI biopsy targets were identified, of which 206 (51.2%) were biopsied with the MRI-TRUS TBx and 196 (48.8%) with the MRI In-bore TBx technique. Per-patient PCa and csPCa detection rates were 140/223 (62.8%) and 97/223 (43.5%), respectively. PCa-DR was 73/117 (62.4%) and 67/106 (63.2%) for MRI-TRUS and MRI In-Bore TBx (

conclusionNo statistically significant difference in the detection rate of MRI In-bore and MRI-TRUS fusion TBx was found. MRI In-bore TBx showed higher per-core percentage of malignant cells. ADVANCES IN KNOWLEDGE: MRI In-bore biopsy might impact risk stratification and patient management considering the higher per-core percentage of malignant cells, especially for patients eligible for active surveillance or focal therapy.

Indexed as

Magnetic Resonance Imaging, InterventionalUltrasonography, InterventionalAgedHumansImage-Guided BiopsyMaleMiddle AgedProstatic NeoplasmsRectumRetrospective Studies

Identifiers

PMID34609900
PMCPMC8978234

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.